Adult Granulosa Cell Tumor Associated With Peritoneal Endometriosis : Is It Fair To Preserve Fertility?

Introduction Granulosa cell tumor is a rare type of cancer, which accounts for 2-5% of ovarian carcinoma and have a better prognosis of ovarian epithelial types. The standard treatment is cytoreductive surgery, but in selected cases it is possible to perform conservative surgery. Some studies have shown endometriosis associated to some types of ovarian cancer, specially endometrioid and clear cells, however, none related to GCT2. Case report: 37-year-old nulliparous woman with a 5 cm solid complex left ovarian mass, underwent a laparoscopic ovarian cystectomy. Adult GCT was confirmed on histology of the left ovary confirmed stage IA disease. The staging laparotomy identified a total of 11 lesions. All were removed and confirmed, in histology, as endometriosis, with no atypical cells. Discussion Granulosa cells tumor affects young patients and fertility preservation is thus an important issue, especially in women without previous pregnancies. However, the role of fertility-sparing surgery remains unclear. Surgery is the primary treatment for adult GCT and complete staging surgery is recommended for patients with early-stage disease.