Malignant Transformation of Endometrioma in a Woman with a History of Ovulation Induction and In Vitro Fertilization

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AI-generated summary by claude@2026-08, 2026-08-07

This case study details a patient with polycystic ovary syndrome and a history of ovulation induction who developed ovarian endometrioid adenocarcinoma within an endometrioma, highlighting the need for gynecological oncologist referral for suspicious endometriomas regardless of CA-125 levels.

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Abstract

License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Our aim is to document a case of endometrioid adenocarcinoma of the ovary found in an endometriotic cyst that was suspected on pelvic ultrasound in a patient with polycystic ovary syndrome, normal Ca125, and a recent history of ovulation induction for IVF. She underwent an exploratory laparotomy with left salpingo-oophorectomy and omental biopsies followed by reexploration, complete staging, andmodified radical abdominal hysterectomy and right salpingo-oophorectomy. An endometrioma described as suspicious for malignancy by an experienced ultrasound examiner should prompt immediate referral to a gynecological oncologist irrespective of Ca125 levels especially in women with a history of ovulation induction and endometriosis. 1.

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endometriosisendometrioma

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last seen: 2026-05-10T11:22:05.459129+00:00
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