Mikania Mikrantha Leaf Extract Mediated Biogenic Synthesis of Magnetic Iron Oxide Nanoparticles: Characterization and Its Antimicrobial Activity Study

With an aim to introduce a new highly potent antimicrobial nanoparticles using an environment-friendly route, he present work reports the green synthesis of iron oxide nanoparticles (Fe 3 O 4 NPs) utilizing Mikania mikrantha leaf extract and its application as efficient antimicrobial agent. The green Fe 3 O 4 NPs have been described by X-beam diffraction (XRD), Ultraviolet-Visible (UV-Vis) spectroscopy, Scanning Electron Microscopy (SEM), Transmission Electron Microscopy (TEM) and Fourier Transform-Infra Red (FT-IR) investigation. The TEM image shows the rhomboidal Fe 3 O 4 NPs with average mean sizes 20.27 nm. The FT-IR investigation proved Fe 3 O 4 NPs have been balanced out through the associations of steroids, terpenoids, flavonoids, phenyl propanoids, phenolic acids and proteins present in the leaf extract. The synthesized Fe 3 O 4 NPs shows a very high antibacterial and antifungal property against 5 bacterial strains such as Bacillus cereus, Acinetobacter johnsonii, Pseudomonas aeruginosa, Achromobacter spanius and Chromobacterium pseudoviolaceum strain, and 4 fungal strains ( Aspergillus niger, Penicillium citirinum, Fusarium oxysporium , and Candida albicans ). The green synthesized iron oxide nanoparticles can interfere metabolic activities of microorganisms which determine its antimicrobial properties and could bring a promising application in the fields of medicine.