Methodological applicability of ultra-low background liquid scintillation counters in low-level tritium measurement | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Methodological applicability of ultra-low background liquid scintillation counters in low-level tritium measurement Jian Shan, Hong-yi Li, Hao zhang, Hui Yang, Nan-nan Wei This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-7783355/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract This study evaluates quench-related uncertainties in low-level 3 H measurement using two ultra-low background liquid scintillation counters, Quantulus 1220 and GCT 6220. High- and low-quench conditions were created by varying sample-to-cocktail ratios, and performance was assessed through detection efficiency, minimum detectable activity (MDA), and stability. Under the relative measurement method with limited quench variation, GCT 6220 achieved higher efficiency, lower background, and lower detection limits. Under the internal standard method with broader quench spans, Quantulus 1220 produced smoother efficiency–quench curves and more stable results. Thus, GCT 6220 is advantageous for sensitivity-demanding scenarios, while Quantulus 1220 is better suited for quench-correction applications. 3H Liquid Scintillation Counting Relative Measurement Method Internal Standard Method Full Text Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. 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