HUBUNGAN USIA MENARCHE DAN INDEKS MASSA TUBUH DENGAN KEJADIAN ENDOMETRIOSIS DI RUMKITAL Dr. RAMELAN SURABAYA
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Abstract
Latar belakang : Endometriosis adalah penyakit ginekologi yang bersifat menahun dan progresif dengan angka kejadiannya mengalami peningkatan dari tahun ke tahun namun penyebab endometriosis sebagian besar masih belum diketahui. Usia menarche dan Indeks Massa Tubuh adalah sebagian faktor resiko yang berhubungan dengan kejadian endometriosis. Tujuan penulisan ini adalah untuk mengetahui hubungan antara usia menarche dan indeks masa tubuh dengan kejadian endometriosis di Rumkital Dr. Ramelan Surabaya. Metode : Penelitian ini merupakan penelitian analitik retrospective dengan pendekatan case control. Kelompok kasus adalah wanita yang menjalani operasi kandungan dengan hasil Patologi Anatomi menunjukkan endometriosis dan kelompok kontrol adalah pasien wanita yang menjalani operasi laparaskopi MOW (Metode Opetratif Wanita). Sampel yang diambil sebanyak 70 responden (35 kasus, 35 kontrol) periode tahun 2017-2018 dengan teknik purposive sampling berdasarkan kriteria inklusi. Variabel dependen adalah endometriosis, sedangkan variabel independen adalah usia menarche dan indeks massa tubuh. Penentuan hubungan menggunakan uji chi square pada tingkat kemaknaan α = 0,05. Hasil : Kejadian endometriosis sebagian besar dialami oleh responden dengan usia menarche 12-13 tahun (62,9%) dan memiliki IMT lebih (60%). Usia menarche tidak memiliki hubungan dengan kejadian endometriosis (p=0,484) sedangkan IMT memiliki hubungan signifikan dengan endometriosis (p=0,005, OR=4,23 ; 95% CI 1,55-11,54; CC=0,366). Kesimpulan: Tidak ada hubungan antara usia menarche dengan kejadian endometriosis dan ada hubungan antara indeks massa tubuh dengan kejadian endometriosis di Rumkital Dr. Ramelan Surabaya.
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SKRIPSI HUBUNGAN USIA MENARCHE… SRI PURWATI P.L.
IR – PERPUSTAKAAN UNIVERSITAS AIRLANGGA
IR – PERPUSTAKAAN UNIVERSITAS AIRLANGGA
DAFTAR ISI
Halaman
SAMPUL DEPAN
SAMPUL DALAM .................................................................................................. i
PRASYARAT GELAR ........................................................................................... ii
PERNYATAAN ORISINALITAS ........................................................................ iii
LEMBAR PERSETUJUAN................................................................................... iv
PENETAPAN PANITIA PENGUJI SKRIPSI ........................................................ v
LEMBAR PENGESAHAN ................................................................................... vi
ABSTRAK ............................................................................................................. ix
ABSTRACT ............................................................................................................... x
DAFTAR ISI .......................................................................................................... xi
DAFTAR TABEL ................................................................................................ xiv
DAFTAR GAMBAR ............................................................................................. xv
DAFTAR LAMPIRAN ........................................................................................ xvi
DAFTAR SINGKATAN, ISTILAH, DAN ARTI LAMBANG ......................... xvii
BAB 1 PENDAHULUAN ................................................................................... 1
1.1. Latar Belakang ...................................................................................... 1
1.2. Rumusan Masalah ................................................................................. 4
1.3. Tujuan Penelitian................................................................................... 4
1.3.1. Tujuan Umum .............................................................................. 4
1.3.2. Tujuan Khusus ............................................................................. 4
1.4. Manfaat Penelitian................................................................................. 5
1.4.1. Teoritis ......................................................................................... 5
1.4.2. Praktis .......................................................................................... 5
BAB 2 TINJAUAN PUSTAKA .......................................................................... 6
2.1. Endometriosis ........................................................................................ 6
2.1.1 Pengertian .................................................................................... 6
2.1.2 Etiologi......................................................................................... 6
2.1.3 Patofisiologi ................................................................................. 7
2.1.4 Epidemiologi dan insidensi ........................................................ 11
2.1.5 Klasifikasi .................................................................................. 12
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SKRIPSI HUBUNGAN USIA MENARCHE… SRI PURWATI P.L.
IR – PERPUSTAKAAN UNIVERSITAS AIRLANGGA
IR – PERPUSTAKAAN UNIVERSITAS AIRLANGGA 2.1.6 Faktor Resiko ............................................................................. 15
2.1.7 Gejala ......................................................................................... 17
2.1.8 Komplikasi ................................................................................. 18
2.1.9 Diagnosis ................................................................................... 19
2.1.10 Diagnosis Banding ................................................................... 21
2.1.11 Penanganan............................................................................... 21
2.1.12 Prognosis .................................................................................. 25
2.2. Konsep dasar Menarche ...................................................................... 25
2.2.1 Definisi....................................................................................... 25
2.2.2 Hubungan Usia Menarche dengan Endometriosis ..................... 26
2.3. Konsep Dasar Indeks Masa Tubuh (IMT)........................................... 26
2.3.1 Definisi....................................................................................... 26
2.3.2 Kategori ..................................................................................... 27
2.3.3 Hubungan IMT dengan Endometriosis ...................................... 27
BAB 3 KONSEPTUAL DAN HIPOTESIS PENELITIAN .............................. 31
3.1. Kerangka Konseptual Penelitian ......................................................... 31
3.2. Hipotesis Penelitian ............................................................................. 33
BAB 4 METODE PENELITIAN ..................................................................... 34
4.1. Jenis Penelitian .................................................................................... 34
4.2. Rancang Bangun Penelitian ................................................................ 34
4.3. Populasi dan Sampel ........................................................................... 35
4.3.1. Populasi ...................................................................................... 35
4.3.2. Sampel ....................................................................................... 35
4.3.3. Besar Sampel ............................................................................. 36
4.3.4. Teknik Pengambilan Sampel ..................................................... 37
4.4. Lokasi dan Waktu Penelitian............................................................... 37
4.4.1. Lokasi Penelitian........................................................................ 37
4.4.2. Waktu Penelitian ........................................................................ 37
4.5. Variabel Penelitian, De finisi Operasional, dan Cara Pengukuran
Variabel ........................................................................................................ 37
4.6. Teknik dan Prosedur Pengumpulan Data ............................................ 39
4.6.1 Teknik Pengumpulan Data......................................................... 39
4.6.2 Prosedur pengumpulan data ....................................................... 39
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SKRIPSI HUBUNGAN USIA MENARCHE… SRI PURWATI P.L.
IR – PERPUSTAKAAN UNIVERSITAS AIRLANGGA
IR – PERPUSTAKAAN UNIVERSITAS AIRLANGGA 4.7. Teknik Pengolahan dan Analisis Data ................................................ 39
4.7.1. Teknik pengolahan data ............................................................. 39
4.7.2. Analisis Data .............................................................................. 41
4.8. Kerangka Operasional ......................................................................... 42
4.9. Ethical Clearance ................................................................................ 43
4.9.1 Anonimity (Tanpa Nama) ........................................................... 43
4.9.2 Confidentialy ( Kerahasian) ....................................................... 43
BAB 5 HASIL PENELITIAN ........................................................................... 44
5.1 Hasil Penelitian ................................................................................... 44
5.1.1 Gambaran Umum ....................................................................... 44
5.1.2 Karakteristik responden ............................................................. 45
5.2 Hasil Penelitian dan Analisis ............................................................... 49
5.2.1 Usia Menarche dengan kejadian endometriosis ......................... 49
5.2.2 Indeks massa tubuh dengan kejadian endometriosis ................. 49
BAB 6 PEMBAHASAN .................................................................................... 52
6.1 Karakteristik Responden ..................................................................... 52
6.2 Hubungan Usia Menarche dengan Endometriosis .............................. 57
6.3 Hubungan Indeks Massa Tubuh dengan Endometriosis ..................... 59
BAB 7 KESIMPULAN DAN SARAN ............................................................. 65
7.1 Kesimpulan.......................................................................................... 65
7.2 Saran .................................................................................................... 65
DAFTAR PUSTAKA ............................................................................................ 67
LAMPIRAN
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