Prevalence of Human Bocavirus in children with acute respiratory illness attending a tertiary care hospital from South India

Prevalence of Human Bocavirus in children with acute respiratory illness attending a tertiary care hospital from South India | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 'https://ssl' : 'http://www') + '.google-analytics.com/ga.js'; var s = document.getElementsByTagName('script')[0]; s.parentNode.insertBefore(ga, s); })(); Skip to main content Preprints Collections Wiley Open Research IET Open Research Ecological Society of Japan All Collections About About Authorea FAQs Contact Us Quick Search anywhere Search for preprint articles, keywords, etc. Search Search ADVANCED SEARCH SCROLL This is a preprint and has not been peer reviewed. Data may be preliminary. 19 June 2025 V1 Latest version Share on Prevalence of Human Bocavirus in children with acute respiratory illness attending a tertiary care hospital from South India Authors : Nisha V , Jaya Lakshmi SS 0000-0002-1837-7776 [email protected] , Leela KV , Harsha Vardhini N , and Subash S Authors Info & Affiliations https://doi.org/10.22541/au.175029846.68839950/v1 315 views 168 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Background: Human Bocavirus (HBoV), is an emerging pathogen associated with respiratory tract infections in children. The pathogen often remains under-recognized in clinical cases due to its overlapping symptoms with other common viral infections like influenza. In India, data on molecular epidemiology of HBoV in respiratory tract infection are scarce. This study aims to determine the molecular prevalence of HBoV among pediatric patients with respiratory symptoms attending a tertiary care hospital and to assess its clinical features in HBoV positive children. Methods: A prospective study was conducted over ten months. Respiratory samples were obtained from children under 12 years old who presented with symptoms of acute respiratory tract infection. Samples were analyzed using multiplex PCR for HBoV. Demographic and clinical data were recorded and analyzed. Results: Out of 108 respiratory samples, HBoV was detected in 3.7% of cases. Co-infection with other viruses was observed in <1% of HBoV-positive cases. The most common symptoms among HBoV-positive children were cough, wheezing, and fever. Most cases occurred in children under 5 years of age, with a marked seasonal peak during November. Conclusions: HBoV is a relatively frequent pathogen in pediatric respiratory infections and often occurs with other respiratory viruses. Advanced molecular diagnostics are crucial for appropriate detection and management, particularly in tertiary care settings where severe cases are referred. Supplementary Material File (manuscript.docx) Download 109.47 KB Information & Authors Information Version history V1 Version 1 19 June 2025 Copyright This work is licensed under a Non Exclusive No Reuse License. Keywords dna extraction infection pathogenesis research and analysis methods respiratory tract Authors Affiliations Nisha V SRM Institute of Science and Technology Faculty of Medicine and Health Sciences View all articles by this author Jaya Lakshmi SS 0000-0002-1837-7776 [email protected] SRM Institute of Science and Technology Faculty of Medicine and Health Sciences View all articles by this author Leela KV SRM Institute of Science and Technology Faculty of Medicine and Health Sciences View all articles by this author Harsha Vardhini N SRM Institute of Science and Technology Faculty of Medicine and Health Sciences View all articles by this author Subash S SRM Institute of Science and Technology Faculty of Medicine and Health Sciences View all articles by this author Metrics & Citations Metrics Article Usage 315 views 168 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Nisha V, Jaya Lakshmi SS, Leela KV, et al. Prevalence of Human Bocavirus in children with acute respiratory illness attending a tertiary care hospital from South India. Authorea . 19 June 2025. DOI: https://doi.org/10.22541/au.175029846.68839950/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. For more information or tips please see 'Downloading to a citation manager' in the Help menu . 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