Neuropathic uterine pain after hysterectomy. A case report.
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A case report describes successful treatment of persistent, severe post-hysterectomy pain, unresponsive to conventional medications, with low-dose amitriptyline, suggesting a neuropathic origin for such gynecologic pain.
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Abstract
BACKGROUND: Neuropathic pain arises when there is damage to or dysfunction of the nervous system. Diabetic neuropathy, postherpetic neuralgia and phantom limb pain are common types of neuropathic pain. It is not commonly recognized in gynecologic practice. CASE: A patient underwent a hysterectomy for a tuboovarian abscess and underlying endometriosis. Despite maximal dosing with conventional pain medications, she continued to have significant pain that had not been present following prior surgeries. Use of low-dose amitriptyline successfully treated the pain, with no sequelae. CONCLUSION: Persistent pain following gynecologic surgery that does not respond to conventional therapy may have a neuropathic origin. Attention to appropriate history and physical examination may lead to an increase in the diagnosis of neuropathic pain in gynecology patients. This may have implications for persistent pain in other gynecologic diseases.
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Cited by (1)
- Pelvic Pain 2020
Cited by (1)
- Pelvic Pain 2020
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- europepmc
- last seen: 2026-09-27T09:11:36.575535+00:00
- openalex
- last seen: 2026-06-10T17:14:06.276822+00:00
- pubmed
- last seen: 2026-05-13T22:12:50.257867+00:00
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