Analysis on clinical,pathological,and immunohistochemical characteristics of 65 cases with endometrial cancer during premenopausal period

Objective: To analyze the clinical,pathological and immunohistochemical characteristics of endometrial cancer during premenopausal period. Methods: A total of 138 patients with endometrial cancer in the hospital were divided into premenopausal group and postmenopausal group from May 2008 to May 2013; and the clinical,pathological and immunohistochemical characteristics were analyzed retrospectively. Results: There were significant differences in incidence rates of vaginal bleeding badly,obesity,infertility,and adenomyosis between the two groups( P 0. 05),there was no significance difference in other clinical manifestations( P 0. 05); there were significant differences in clinical stage,pathological type,degree of cell differentiation,the infiltration of muscular and immunohistochemical ER,PR expressions between the two groups. Conclusion: The type of most endometrial cancer in premenopausal women is endometrial adenocarcinoma and stage I,muscular infiltrate shallow,tumor cell differentiation degree is high,the positive rates of ER and PE are high.