Abstract
Endometrial stromal sarcoma (ESS) is a rare malignant tumor of endometrium compromising 10 % of all uterine sarcomas occurring in perimenopausal age group. Patient’s mainly present with symptoms of abnormal vaginal bleeding, abdominal pain and rapid enlargement of abdomen. They are usually mistaken as leiomyoma, adenomyosis or intrauterine polyps and majority of time they are diagnosed postoperatively on histopathology. These tumours are mostly positive for both estrogen and progesterone receptors (ER/PR). Here we describe seven cases of ESS and their clinical course.
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References
- 1. Tavassoli FA, Devilee P. WHO Classification of Pathology and genetics of tumours of the breast and female genital organs. In: Tavassoli FA, Devilee P, editors, Lyon, France: IARC Press; 2003. p. 233-6. 2. Beer, T.W.; Buchanan, R.; Buckley, C.H. Uterine stromal sarcoma following tamoxifen treatment. J. Clin. Pathol. 1995, 48, 596. [CrossRef] 3. Toprak U, Paaolu E, Karademir MA, Gülbay M. Sonographic, CT, and MRI findings of endometrial stromal sarcoma located in the myometrium and associated with peritoneal inclusion cyst. AJR Am J Roentgenol2004;182:1531-3. 4. NCCN clinical practice guidelines in oncology. Soft tissue sarcoma. Version 2. 2020. National Comprehensive Cancer Network, Inc.;2020. 5. B.-L. L. Seagle, A. Shilpi, S. Buchanan, C. Goodman, and S. Shahabi, "Low-grade and high-grade endometrial stromal sarcoma: A National Cancer Database study," Gynecologic Oncology, vol. 146, no. 2, pp. 254–262, 201 6. Zhu XQ, Shi YF, Cheng X, Zhao CL, Wu YZ. Detail Immunohistichemical markers in differential diagnosis of endometrial stromal sarcoma and cellular leomyoma. Gynaecol Oncol 2004;92:71-9 7. Halbwed I, Ullmann R, Kremser ML, Man YG, Moud NI, Lax S, et al. Chromosomal alterations in low-grade endometrial stromal sarcoma and undifferentiated endometrial sarcoma as detected by comparative genomic hybridization. Gynecol Oncol 2005;2:582-7. 8. Agoff SN, Grieco VS, Garcia R, Gown AM Immunohistochemical distinction of endometrial stromal sarcoma and cellular leiomyoma. Appl Immunohistochem Mol Morphol2001;9:164-9. 9. Sumathi VP, McCluggage WG. CD 10 is useful in demonstrating endometrial stroma at ectopic sites and in confirming a diagnosis of endometriosis. J Clin Pathol2002;55:391-2. 10. Spano JP, Soria JC, Kambouchner M, Piperno-Neuman S, Morin F, Morere JF, et al. Long-term survival of patients given hormonal therapy for metastatic endometrial stromal sarcoma. Med Oncol 2003;20:87-93. 11. Alkasi O, Meinhold-Heerlein I, Zaki R, Fasching P, Maass N, Jonat W, et al. Long-term disease-free survival after hormonal therapy of a patient with recurrent low grade endometrial stromal sarcoma: A case report. Arch GynecolObstet2009;279:57-60. 12. Malouf GG, Duclos J, Rey A, Duvillard P, Lazar V, Haie-Meder C, et al. Impact of adjuvant treatment modalities on the management of patients with stages I-II endometrial stromal sarcoma Ann Oncol 2010;21:2102-6. 13. Bodner K, Adler BB, Obermair A, Windbichler G, Petru E, Mayerhofer S, et al. Prognostic parameters in endometrial stromal sarcoma: A clinicopathologic study in 31 patients. Gynecol Oncol 2001;81:160S-5S.