Endometrial cancer as an estrogen-progesterone target

ESTROGEN and progesterone have long stood as the sole controlling agents in the growth of the endometrium, and both agents have long been available for therapeutic purposes in the form of chemically modified preparations of high potency. It has proved possible and profitable to reproduce the sequence of morphologic changes that are normal for the menstrual cycle, to produce pregnancy-like changes that are symptomatically beneficial in the treatment of endometriosis, and to produce abnormal alterations, in which stroma and glands are not in phase with each other, to prevent the implantation of a fertilized ovum.Another and even greater triumph . . .