Conservative Surgery of Deep Bowel Endometriosis

In: Clinical Management of Bowel Endometriosis · 2020 · pp. 119–133 · doi:10.1007/978-3-030-50446-5_11 · W3083385329
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For sigmoid deep endometriosis, short bowel resections are recommended, while for rectal lesions, conservative excision is preferred to avoid complications.

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This paper discusses the management of deep bowel endometriosis, focusing on how deep endometriosis is defined, the diagnostic pitfalls, and postoperative complications alongside outcomes for pain, infertility, and quality of life. It argues that recurrence and complication rates after conservative excision versus bowel resection are not obviously different even when endometriotic nests remain up to 5 cm from a nodule, and proposes an explanation using a genetic-epigenetic model with an inner stable core, a reversible epigenetic peripheral zone, and a fibrotic layer. The chapter’s key practical conclusions are that for sigmoid deep endometriosis, short bowel resections should be used liberally due to fewer life-long complications and greater technical ease, whereas for rectal and low rectal disease conservative excision (including discoid excision) is preferred and rectum resection should generally be avoided, with rectum resections largely reserved for very large lesions. The paper does not provide a new study dataset but synthesizes existing knowledge and technical discussions to justify these recommendations, and it acknowledges challenges such as diagnostic accuracy and feasibility of conservative excision. This paper is centrally about endometriosis — specifically conservative versus resective surgical strategies for deep bowel endometriosis of the sigmoid and rectum.

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Abstract

The management of deep endometriosis of the bowel remains debated. A discussion of the management needs to define deep endometriosis, to understand the accuracy and pitfalls of the diagnosis, and to consider postoperative complications, for the rest of the life bladder, bowel and sexual problems together with the results concerning pain, infertility and quality of life. It is well established that the recurrence rates and complication rates after conservative excision and after a bowel resection are not obviously different notwithstanding remaining nests of endometrium like cells up to 5 cm from a nodule. Considering the genetic-epigenetic pathophysiology of endometriosis, we explain this apparent discrepancy in recurrence rates by postulating that deep endometriosis is composed of an inner core of endometriotic cells with stable genetic-epigenetic alterations, surrounded by metaplastic endometrium like cells with reversible epigenetic alterations and a fibrotic zone. With our knowledge of today we suggest that for deep endometriosis of the sigmoid, short bowel resections should be liberally used. A sigmoid bowel resection is associated with little postoperative and for the rest of the life complications, and is technically much easier than a conservative excision, which moreover is often not feasible. For rectum and low rectum deep endometriosis lesions a conservative excision is the preferred technique and a rectum resection should be avoided. Today almost all deep endometriosis lesions of the rectum can be treated conservatively by excision, eventually by a discoid excision. It is discussed why rectum resections should be avoided. Rectum resections have progressively become obsolete except for the very large lesions, for which a short resection should be performed. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

References

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We thank Muna Tahlak, Latiffa, Dubai for facilitating this collaboration. Conflict of Interest: None of the authors have a conflict of interest to declare. Financial support: None. Author information Authors and Affiliations Editor information Editors and Affiliations Rights and permissions Copyright information © 2020 Springer Nature Switzerland AG About this chapter Cite this chapter Koninckx, P.R. et al. (2020). Conservative Surgery of Deep Bowel Endometriosis. In: Ferrero, S., Ceccaroni, M. (eds) Clinical Management of Bowel Endometriosis. Springer, Cham. https://doi.org/10.1007/978-3-030-50446-5_11 Download citation DOI: https://doi.org/10.1007/978-3-030-50446-5_11 Published: Publisher Name: Springer, Cham Print ISBN: 978-3-030-50445-8 Online ISBN: 978-3-030-50446-5 eBook Packages: MedicineMedicine (R0)

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