Clinical and CT Features of the COVID-19 Infection: Comparison among different four age groups

Abstract Purpose: To compare and analyze the clinical and CT features of coronavirus disease 2019 (COVID-19) among different four age groups.Methods: 97 patients with chest CT examination and positive reverse transcriptase polymerase chain reaction test (RT-PCR) from January 17, 2019 to February 21, 2020 were reviewed. The first clinical symptoms of each patient were collected and their first chest CT images were observed by dividing them into 4 groups according to age: junior, young, middle-age, and senior.Results: Comorbidities are more common in the senior group. Cluster onset is more common in junior group and senior group. Older patients have shown higher incidence with the highest clinical classification of severe or critical in these 4 groups. Senior patients have a higher incidence of large/multiple ground-glass opacity (GGO). Junior patients are mostly negative for chest CT or involve only one lobe of the lung. While in elderly patients, older patients have a higher incidence of involvement of 4 or 5 lung lobes. The frequency of lobe involvement also has significant differences in 4 different age groups. Conclusion: The clinical and imaging features of patients in different age groups are significantly different. Understanding of these features correctly and making the correct diagnosis promptly is of great significance for the scanning, diagnosis and prevention of COVID-19.