Infection Prevention Compliance and Associated Factors among Nurses in Hemodialysis Units for Chronic Kidney Disease Patients in Addis Ababa, Ethiopia: A Cross-Sectional Study

Infection Prevention Compliance and Associated Factors among Nurses in Hemodialysis Units for Chronic Kidney Disease Patients in Addis Ababa, Ethiopia: A Cross-Sectional Study | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Infection Prevention Compliance and Associated Factors among Nurses in Hemodialysis Units for Chronic Kidney Disease Patients in Addis Ababa, Ethiopia: A Cross-Sectional Study Tigle Nadew, Hussen Mekonnen, Abigiya Wondimagegnehu This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-8505954/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Background: Patients with chronic renal disease undergoing hemodialysis are more vulnerable to infection due to the nature of their illness and the type of treatment they get. Medical practitioners in many developing countries, including Ethiopia, have low levels of adherence to infection prevention methods despite the rise in highly contagious illnesses. Effective interventions can be developed by closely assessing the elements that contribute to this problem. Methods: A facility-based cross-sectional study was carried out among nurses working at dialysis units for chronic kidney disease patients in Addis Ababa. A total of 251 nurses were included. A structured self-administered questionnaire, which has eight components and a checklist, were used for data collection. Confirmatory Factor Analysis was used to generate a composite index upon each component of compliance since they have unequal weight to infection preventation. Descriptive statistics and regresson analysis were used then. Finally, logistic regression was done and adjusted odds ratio (AOR) with a 95% confidence interval was estimated in the final model. P-values of below 0.05 were regarded as significantly associated variables. Results: The result showed that 125 nurses 54.34% were compliant to infection prevention and control practices. The multivariable logistic regression result indicates, monthly salary10,000.00-20,000.00) [(AOR:3.23 ,95%CI (1.20-8.70)], frequency of duty [(AOR: 0.48 ,95%CI (0.25-0.93)], and work environment factor [(AOR: 6.57 ,95%CI (3.38-12.78)] were predictors of infection prevention compliance. Conclusion: Infection prevention compliance was not sufficiently practiced among dialysis unit nurses. Monthly salary, frequency of duty and work environment factors were factors associated with infection prevention compliance. Thus, intervention should focus on encouraging nurses by giving competitive benefit through salary increment, decreasing workload and creating good work environmental factors by ensuring sufficient and sustainable resources. Full Text Additional Declarations No competing interests reported. Supplementary Files Supplementary.pdf Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-8505954","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":587621191,"identity":"dbe55348-664e-4e23-a5b9-5e24e882d5b5","order_by":0,"name":"Tigle Nadew","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA/ElEQVRIiWNgGAWjYDACZgbGAwwVEnJszMwHHwD5PHyEdPAwMzAcYDhjYczP3pZsABJgI6gFiA8wtlUkzuw5YyYBEiGoxZ6d/cKBD2wSjBtu5JhVfs2xk2FjYH746AZeh/EUHJzBI8FscCOt7LbstmSgw9iMjXPwa0k4zCMhwWZwI3nbbcltzEAtPGzSBLX8MZDgMbiRYFYsua2eGC3sBw4zJEhISPYcMWP8uO0wEVoO8zAc7DkgYQAKZGnGbcd52JgJ+IW9//jDBz//1dW3AaPy489t1fb87M0PH+PTArTHAM5k5gGTeJWD7XkAZzL+IKh6FIyCUTAKRiIAAO3KRZ5NscaqAAAAAElFTkSuQmCC","orcid":"","institution":"Addis Ababa University","correspondingAuthor":true,"prefix":"","firstName":"Tigle","middleName":"","lastName":"Nadew","suffix":""},{"id":587621192,"identity":"b17d5e17-22b1-4e13-a07e-8b8e7f37d19f","order_by":1,"name":"Hussen Mekonnen","email":"","orcid":"","institution":"Addis Ababa University","correspondingAuthor":false,"prefix":"","firstName":"Hussen","middleName":"","lastName":"Mekonnen","suffix":""},{"id":587621193,"identity":"0d4e8ca8-aafb-4972-80a7-47df09fedf35","order_by":2,"name":"Abigiya Wondimagegnehu","email":"","orcid":"","institution":"Addis Ababa University","correspondingAuthor":false,"prefix":"","firstName":"Abigiya","middleName":"","lastName":"Wondimagegnehu","suffix":""}],"badges":[],"createdAt":"2026-01-03 09:53:13","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-8505954/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-8505954/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":104739211,"identity":"a241e5f5-99a6-410f-be24-bdfb9af6d064","added_by":"auto","created_at":"2026-03-16 15:57:51","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":478682,"visible":true,"origin":"","legend":"","description":"","filename":"Revised3InfectionPreventionComplianceandAssociatedHemodialysisWN2.pdf","url":"https://assets-eu.researchsquare.com/files/rs-8505954/v1_covered_cfd98d56-972b-4cb8-bd5b-ba29f5b8c49b.pdf"},{"id":102175321,"identity":"111aaf01-d4ab-4181-a5a9-a712ea3da2a6","added_by":"auto","created_at":"2026-02-09 06:05:34","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"supplement","size":648792,"visible":true,"origin":"","legend":"","description":"","filename":"Supplementary.pdf","url":"https://assets-eu.researchsquare.com/files/rs-8505954/v1/72eacc67e31be129500c29dc.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"Infection Prevention Compliance and Associated Factors among Nurses in Hemodialysis Units for Chronic Kidney Disease Patients in Addis Ababa, Ethiopia: A Cross-Sectional Study","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"","lastPublishedDoi":"10.21203/rs.3.rs-8505954/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-8505954/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003e\u003cstrong\u003eBackground:\u003c/strong\u003e Patients with chronic renal disease undergoing hemodialysis are more vulnerable to infection due to the nature of their illness and the type of treatment they get. Medical practitioners in many developing countries, including Ethiopia, have low levels of adherence to infection prevention methods despite the rise in highly contagious illnesses. Effective interventions can be developed by closely assessing the elements that contribute to this problem.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eMethods:\u003c/strong\u003e A facility-based cross-sectional study was carried out among nurses working at dialysis units for chronic kidney disease patients in Addis Ababa. A total of 251 nurses were included. A structured self-administered questionnaire, which has eight components and a checklist, were used for data collection. Confirmatory Factor Analysis was used to generate a composite index upon each component of compliance since they have unequal weight to infection preventation. \u0026nbsp;Descriptive statistics and regresson analysis were used then. Finally, logistic regression was done and adjusted odds ratio (AOR) with a 95% confidence interval was estimated in the final model. P-values of below 0.05 were regarded as significantly associated variables.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eResults: \u003c/strong\u003e\u0026nbsp;The result showed that 125 nurses 54.34% were compliant to infection prevention and control practices. The multivariable logistic regression result indicates, monthly salary10,000.00-20,000.00) [(AOR:3.23 ,95%CI (1.20-8.70)], frequency of duty [(AOR: 0.48 ,95%CI (0.25-0.93)], and work environment factor [(AOR: 6.57 ,95%CI (3.38-12.78)] were predictors of infection prevention compliance.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConclusion:\u003c/strong\u003e Infection prevention compliance was not sufficiently practiced among dialysis unit nurses. Monthly salary, frequency of duty and work environment factors were factors associated with infection prevention compliance. Thus, intervention should focus on encouraging nurses by giving competitive benefit through salary increment, decreasing workload and creating good work environmental factors by ensuring sufficient and sustainable resources.\u003c/p\u003e","manuscriptTitle":"Infection Prevention Compliance and Associated Factors among Nurses in Hemodialysis Units for Chronic Kidney Disease Patients in Addis Ababa, Ethiopia: A Cross-Sectional Study","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2026-02-09 06:05:29","doi":"10.21203/rs.3.rs-8505954/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"f90aa16e-ae95-4e4f-a449-ef019fdc2f5b","owner":[],"postedDate":"February 9th, 2026","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[],"tags":[],"updatedAt":"2026-03-16T15:56:55+00:00","versionOfRecord":[],"versionCreatedAt":"2026-02-09 06:05:29","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-8505954","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-8505954","identity":"rs-8505954","version":["v1"]},"buildId":"XKTyCvWXoU3ODBz1xrDgd","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}