Case report of Fibroadenoma in axillary accessory breast

Case report of Fibroadenoma in axillary accessory breast | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Case Report Case report of Fibroadenoma in axillary accessory breast Ahmed Mohammed Nour, Mohammed Saad Aldarami, Hanan Albishi This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-6832141/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Introduction Accessory breast tissue, also known as ectopic or supernumerary breast tissue, is a rare developmental anomaly resulting from incomplete regression of the mammary ridge during embryogenesis. Fibroadenoma is a benign tumor commonly arising in breast tissue but is rarely reported in accessory breast tissue. (1) Case report This case report presents a 22-year-old female with a fibroadenoma in a right axillary accessory breast. The diagnosis was accomplished through clinical examination that revealed an accessory breast that contains a lump, ultrasound imaging supported the diagnosis and surgical excision was successfully performed. Discussion Accessory breast tissue arises due to incomplete regression of the embryonic mammary ridge. It may remain asymptomatic or present with cyclical changes, pain, or a palpable mass. Fibroadenomas are rare in accessory breast tissue and pose diagnostic challenges due to their unusual location. Figures Figure 1 Figure 2 Figure 3 Figure 4 Figure 5 Introduction Accessory breast tissue occurs in approximately 1–6% of the population and is most commonly located along the “milk line,” which extends from the axilla to the groin. ( 1 ) Fibroadenomas in accessory breast tissue are very rare. Patients may present with a mass, discomfort, or cosmetic concerns. This report highlights the importance of recognising accessory breast conditions and differentiating benign from malignant lesions. Case Presentation A 23-year-old female presented with a painless, gradually increasing mass in the right axillary region for the past 3 years. She had no history of trauma, infection, nipple discharge, or constitutional symptoms. Her medical and family history were unremarkable. Clinical Examination : Accessory breast in the right axilla Within it A firm, well-circumscribed, wider mobile mass approximately 3 × 2 cm. The overlying skin was normal . No palpable lymphadenopathy in the axillary or supraclavicular regions bilaterally and normal left breast and left axillary examination. Figure 1 Investigations Ultrasound of the right axillary mass revealed a well-defined hypoechoic lesion with smooth margins, in an accessory right breast consistent with a fibroadenoma. Figure 2 Management Surgical excision was performed under general anaesthesia. An elliptical incision was made on the accessory breast, and the mass along with the accessory breast tissue and excess skin, was excised. The procedure was performed as a day surgery and was uneventful. Figure 3 and Fig. 4 Postoperative Course The patient recovered well, with no complications. Follow-up at 2 weeks showed no residual symptoms and healed wound. Figure 4 Postoperative histopathology confirmed fibroadenoma within accessory breast tissue. Figure 5 Discussion Accessory breast tissue arises due to incomplete regression of the embryonic mammary ridge. ( 1 ) It may remain asymptomatic or present with cyclical changes, pain, or a palpable mass. Fibroadenomas are rare in accessory breast tissue and pose diagnostic challenges due to their unusual location. ( 1 , 2 ) Imaging, particularly ultrasound, aids in identifying benign lesions, and FNAC or core needle biopsy provides cytological confirmation. Complete excision is curative, with histopathology ensuring the exclusion of malignancy. ( 6 ) This case showed the importance of recognizing accessory breast tissue anomalies and distinguishing fibroadenomas from other pathologies such as lipomas, lymphadenopathy, or malignant lesions. ( 7 ) Conclusion Fibroadenomas in accessory breast tissue are rare but should be considered in young females presenting with axillary masses. Surgical excision provides symptom relief, cosmetic satisfaction, and histological confirmation. ( 4 , 5 ) Early diagnosis and management are crucial to avoid complications and ensure optimal patient outcomes. Declarations Ethical approval : Approval of the study and publication was obtained from the Ethical committee at King Abdullah Hospital. No.BIS-24-0001028072024 Availability of data and materials: The datasets used and/or analysed during the current study are available from the corresponding author on reasonable request. Conflict of interest: No competing interests. Funding: No funding for this case report. Authors contribution: AN, reviewed and collected the data and performed the surgery and collected the data of the radiology and histopathology. M S and H A A, wrote the manuscript and the final review was performed by A M N. All authors read and approved the final manuscript. Consent: Written consent was taken from the patient for publishing the case report References Goyal S, Puri T, Gupta R, et al. Accessory breast tissue presenting as axillary swelling. Case Reports in Surgery. 2013;2013:812419. doi:10.1155/2013/812419. Kumar N, Sahu S, Pai MC, et al. Fibroadenoma in accessory axillary breast tissue: A rare entity. Indian Journal of Surgery. 2015;77(Suppl 3):1275-1276. doi:10.1007/s12262-014-1064-1. Ramakrishnaiah VP, Abraham R. Fibroadenoma in axillary accessory breast tissue. BMJ Case Reports. 2016;2016:bcr2016215072. doi:10.1136/bcr-2016-215072. Koo JH, Lee JS, Kim YH, et al. Accessory mammary tissue and its relevance in breast cancer: A systematic review. World Journal of Surgical Oncology. 2017;15(1):129. doi:10.1186/s12957-017-1207-x. Gandhi V, Sharma D, Paliwal N, et al. Fibroadenoma in ectopic breast tissue in the axilla: A rare case report. Annals of Pathology and Laboratory Medicine. 2017;4(6):A750-A752. Velanovich V, Szymanski W. Axillary breast tissue, hyperplasia, and breast cancer: A review. The American Surgeon. 1999;65(12):1121-1125. Tan M, Lam HC, Chua JH. Ectopic breast tissue in the axilla. Singapore Medical Journal. 1998;39(11):504-505. Additional Declarations No competing interests reported. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-6832141","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Case Report","associatedPublications":[],"authors":[{"id":470047433,"identity":"b3598a9c-e049-4a96-899b-3ca0d6c7b3cb","order_by":0,"name":"Ahmed Mohammed 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Albishi","email":"","orcid":"","institution":"king Abdullah Hospital","correspondingAuthor":false,"prefix":"","firstName":"Hanan","middleName":"","lastName":"Albishi","suffix":""}],"badges":[],"createdAt":"2025-06-05 22:08:17","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-6832141/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-6832141/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":84547837,"identity":"4fb39624-913e-448f-825a-48b02e8bfad3","added_by":"auto","created_at":"2025-06-13 09:34:36","extension":"png","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":37629,"visible":true,"origin":"","legend":"\u003cp\u003eAccessory breast in the right axilla\u003c/p\u003e","description":"","filename":"floatimage1.png","url":"https://assets-eu.researchsquare.com/files/rs-6832141/v1/64bc121d81c3b7ca8a8c7d14.png"},{"id":84547486,"identity":"6bb0767a-2a5e-430a-8484-264d75acc689","added_by":"auto","created_at":"2025-06-13 09:26:36","extension":"png","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":154925,"visible":true,"origin":"","legend":"\u003cp\u003eUltrasound image shows fibroadenoma in the accessory breast\u003c/p\u003e","description":"","filename":"floatimage2.png","url":"https://assets-eu.researchsquare.com/files/rs-6832141/v1/ab92252c2ef9206abd99e5dc.png"},{"id":84547490,"identity":"e847216d-c143-42ab-b82d-99bc494ed13f","added_by":"auto","created_at":"2025-06-13 09:26:36","extension":"png","order_by":3,"title":"Figure 3","display":"","copyAsset":false,"role":"figure","size":195608,"visible":true,"origin":"","legend":"\u003cp\u003eThe excised mass and skin\u003c/p\u003e","description":"","filename":"floatimage3.png","url":"https://assets-eu.researchsquare.com/files/rs-6832141/v1/f492584ac265027126dd127a.png"},{"id":84547484,"identity":"18717f68-8a8d-45bd-87f1-47a763ae8683","added_by":"auto","created_at":"2025-06-13 09:26:36","extension":"png","order_by":4,"title":"Figure 4","display":"","copyAsset":false,"role":"figure","size":67901,"visible":true,"origin":"","legend":"\u003cp\u003eTwo weeks after surgery\u003c/p\u003e","description":"","filename":"floatimage4.png","url":"https://assets-eu.researchsquare.com/files/rs-6832141/v1/f1bb1277060fac7873bfb28a.png"},{"id":84548570,"identity":"0ec6a8ff-83c9-46e2-8b92-565675a24ee7","added_by":"auto","created_at":"2025-06-13 09:42:37","extension":"png","order_by":5,"title":"Figure 5","display":"","copyAsset":false,"role":"figure","size":319691,"visible":true,"origin":"","legend":"\u003cp\u003ethe microscopic appearance of the breast tissue and fibroadenoma\u003c/p\u003e","description":"","filename":"floatimage5.png","url":"https://assets-eu.researchsquare.com/files/rs-6832141/v1/3f4ab9c54a9eeea2fc3f4d01.png"},{"id":84548877,"identity":"b1eeaf98-8205-4414-8fc5-e5c7a5d6e5c3","added_by":"auto","created_at":"2025-06-13 09:50:38","extension":"pdf","order_by":0,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":1105058,"visible":true,"origin":"","legend":"","description":"","filename":"manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-6832141/v1/53bc23df-735d-4f75-a38e-c4852f508cf4.pdf"}],"financialInterests":"No competing interests reported.","formattedTitle":"Case report of Fibroadenoma in axillary accessory breast","fulltext":[{"header":"Introduction","content":"\u003cp\u003eAccessory breast tissue occurs in approximately 1\u0026ndash;6% of the population and is most commonly located along the \u0026ldquo;milk line,\u0026rdquo; which extends from the axilla to the groin.\u003csup\u003e(\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e)\u003c/sup\u003e Fibroadenomas in accessory breast tissue are very rare. Patients may present with a mass, discomfort, or cosmetic concerns. This report highlights the importance of recognising accessory breast conditions and differentiating benign from malignant lesions.\u003c/p\u003e"},{"header":"Case Presentation","content":"\u003cp\u003eA 23-year-old female presented with a painless, gradually increasing mass in the right axillary region for the past 3 years. She had no history of trauma, infection, nipple discharge, or constitutional symptoms. Her medical and family history were unremarkable.\u003c/p\u003e \u003cdiv id=\"Sec3\" class=\"Section2\"\u003e \u003ch2\u003e\u003cb\u003eClinical Examination\u003c/b\u003e:\u003c/h2\u003e \u003cp\u003eAccessory breast in the right axilla\u003c/p\u003e \u003cp\u003eWithin it A firm, well-circumscribed, wider mobile mass approximately 3 \u0026times; 2 cm.\u003c/p\u003e \u003cp\u003eThe overlying skin was normal .\u003c/p\u003e \u003cp\u003eNo palpable lymphadenopathy in the axillary or supraclavicular regions bilaterally and normal left breast and left axillary examination. Figure \u003cspan refid=\"Fig2\" class=\"InternalRef\"\u003e1\u003c/span\u003e\u003c/p\u003e \u003cp\u003e \u003c/p\u003e \u003c/div\u003e\n\u003ch3\u003eInvestigations\u003c/h3\u003e\n\u003cp\u003eUltrasound of the right axillary mass revealed a well-defined hypoechoic lesion with smooth margins, in an accessory right breast consistent with a fibroadenoma. Figure\u0026nbsp;2\u003c/p\u003e \u003cp\u003e \u003c/p\u003e\n\u003ch3\u003eManagement\u003c/h3\u003e\n\u003cp\u003e \u003c/p\u003e \u003cp\u003eSurgical excision was performed under general anaesthesia. An elliptical incision was made on the accessory breast, and the mass along with the accessory breast tissue and excess skin, was excised. The procedure was performed as a day surgery and was uneventful. Figure\u0026nbsp;3 and Fig.\u0026nbsp;\u003cspan refid=\"Fig3\" class=\"InternalRef\"\u003e4\u003c/span\u003e\u003c/p\u003e \n\u003ch3\u003ePostoperative Course\u003c/h3\u003e\n\u003cp\u003eThe patient recovered well, with no complications. Follow-up at 2 weeks showed no residual symptoms and healed wound. Figure 4\u003c/p\u003e\n\u003cp\u003ePostoperative histopathology confirmed fibroadenoma within accessory breast tissue. Figure 5\u003c/p\u003e"},{"header":"Discussion","content":"\u003cp\u003eAccessory breast tissue arises due to incomplete regression of the embryonic mammary ridge.\u003csup\u003e(\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e)\u003c/sup\u003e It may remain asymptomatic or present with cyclical changes, pain, or a palpable mass. Fibroadenomas are rare in accessory breast tissue and pose diagnostic challenges due to their unusual location.\u003csup\u003e(\u003cspan citationid=\"CR1\" class=\"CitationRef\"\u003e1\u003c/span\u003e, \u003cspan citationid=\"CR2\" class=\"CitationRef\"\u003e2\u003c/span\u003e)\u003c/sup\u003e\u003c/p\u003e \u003cp\u003eImaging, particularly ultrasound, aids in identifying benign lesions, and FNAC or core needle biopsy provides cytological confirmation. Complete excision is curative, with histopathology ensuring the exclusion of malignancy.\u003csup\u003e(\u003cspan citationid=\"CR6\" class=\"CitationRef\"\u003e6\u003c/span\u003e)\u003c/sup\u003e\u003c/p\u003e \u003cp\u003eThis case showed the importance of recognizing accessory breast tissue anomalies and distinguishing fibroadenomas from other pathologies such as lipomas, lymphadenopathy, or malignant lesions.\u003csup\u003e(\u003cspan citationid=\"CR7\" class=\"CitationRef\"\u003e7\u003c/span\u003e)\u003c/sup\u003e\u003c/p\u003e"},{"header":"Conclusion","content":"\u003cp\u003eFibroadenomas in accessory breast tissue are rare but should be considered in young females presenting with axillary masses. Surgical excision provides symptom relief, cosmetic satisfaction, and histological confirmation.\u003csup\u003e(\u003cspan citationid=\"CR4\" class=\"CitationRef\"\u003e4\u003c/span\u003e, \u003cspan citationid=\"CR5\" class=\"CitationRef\"\u003e5\u003c/span\u003e)\u003c/sup\u003e Early diagnosis and management are crucial to avoid complications and ensure optimal patient outcomes.\u003c/p\u003e"},{"header":"Declarations","content":"\u003cp\u003e\u003cstrong\u003eEthical approval\u003c/strong\u003e:\u0026nbsp;\u003c/p\u003e\n\u003cp\u003eApproval of the study and publication was obtained from the Ethical committee at King Abdullah Hospital. \u0026nbsp;No.BIS-24-0001028072024\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAvailability of data and materials:\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eThe datasets used and/or analysed during the current study are available from the corresponding author on reasonable request.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConflict of interest:\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003e\u0026nbsp;No competing interests.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eFunding:\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eNo funding for this case report.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eAuthors contribution:\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eAN, reviewed and collected the data and performed the surgery and collected the data of the radiology and histopathology. M S and H A A, wrote the manuscript and the final review was performed by A M N.\u0026nbsp; All authors read and approved the final manuscript.\u003c/p\u003e\n\u003cp\u003e\u003cstrong\u003eConsent:\u0026nbsp;\u003c/strong\u003e\u003c/p\u003e\n\u003cp\u003eWritten consent was taken from the patient for publishing the case report\u003c/p\u003e"},{"header":"References","content":"\u003col\u003e\n \u003cli\u003eGoyal S, Puri T, Gupta R, et al. Accessory breast tissue presenting as axillary swelling. Case Reports in Surgery. 2013;2013:812419. doi:10.1155/2013/812419.\u003c/li\u003e\n \u003cli\u003eKumar N, Sahu S, Pai MC, et al. Fibroadenoma in accessory axillary breast tissue: A rare entity. Indian Journal of Surgery. 2015;77(Suppl 3):1275-1276. doi:10.1007/s12262-014-1064-1.\u003c/li\u003e\n \u003cli\u003eRamakrishnaiah VP, Abraham R. Fibroadenoma in axillary accessory breast tissue. BMJ Case Reports. 2016;2016:bcr2016215072. doi:10.1136/bcr-2016-215072.\u003c/li\u003e\n \u003cli\u003eKoo JH, Lee JS, Kim YH, et al. Accessory mammary tissue and its relevance in breast cancer: A systematic review. World Journal of Surgical Oncology. 2017;15(1):129. doi:10.1186/s12957-017-1207-x.\u003c/li\u003e\n \u003cli\u003eGandhi V, Sharma D, Paliwal N, et al. Fibroadenoma in ectopic breast tissue in the axilla: A rare case report. Annals of Pathology and Laboratory Medicine. 2017;4(6):A750-A752.\u003c/li\u003e\n \u003cli\u003eVelanovich V, Szymanski W. Axillary breast tissue, hyperplasia, and breast cancer: A review. The American Surgeon. 1999;65(12):1121-1125.\u003c/li\u003e\n \u003cli\u003eTan M, Lam HC, Chua JH. Ectopic breast tissue in the axilla. Singapore Medical Journal. 1998;39(11):504-505.\u003c/li\u003e\n\u003c/ol\u003e"}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":true,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":true,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":false,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"","lastPublishedDoi":"10.21203/rs.3.rs-6832141/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-6832141/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003ch2\u003eIntroduction\u003c/h2\u003e \u003cp\u003eAccessory breast tissue, also known as ectopic or supernumerary breast tissue, is a rare developmental anomaly resulting from incomplete regression of the mammary ridge during embryogenesis. Fibroadenoma is a benign tumor commonly arising in breast tissue but is rarely reported in accessory breast tissue. (1)\u003c/p\u003e\u003ch2\u003eCase report\u003c/h2\u003e \u003cp\u003eThis case report presents a 22-year-old female with a fibroadenoma in a right axillary accessory breast. The diagnosis was accomplished through clinical examination that revealed an accessory breast that contains a lump, ultrasound imaging supported the diagnosis and surgical excision was successfully performed.\u003c/p\u003e\u003ch2\u003eDiscussion\u003c/h2\u003e \u003cp\u003eAccessory breast tissue arises due to incomplete regression of the embryonic mammary ridge. It may remain asymptomatic or present with cyclical changes, pain, or a palpable mass. Fibroadenomas are rare in accessory breast tissue and pose diagnostic challenges due to their unusual location.\u003c/p\u003e","manuscriptTitle":"Case report of Fibroadenoma in axillary accessory breast","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2025-06-13 09:26:31","doi":"10.21203/rs.3.rs-6832141/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"079c77a5-9b39-4808-9f89-3aad19b2f430","owner":[],"postedDate":"June 13th, 2025","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"posted","subjectAreas":[],"tags":[],"updatedAt":"2025-06-13T09:26:34+00:00","versionOfRecord":[],"versionCreatedAt":"2025-06-13 09:26:31","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-6832141","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-6832141","identity":"rs-6832141","version":["v1"]},"buildId":"8U1c8b4HqxoKbykW_rLl7","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}