Halo sign and reverse halo sign in a patient with primary lung adenocarcinoma; a case report

preprint OA: closed
View at publisher

Abstract

Abstract Introduction: The halo sign and reverse halo sign are two computerized tomography scan views based on the placement of ground glass opacity. These two views have various differential diagnoses, but infections are known to be the most important differential diagnosis in both views. Lung adenocarcinoma, one of the deadliest tumors of both genders, can be included in the differential diagnosis. Nevertheless, we decided to report this case since both of these features were present in the same patient. Case presentation: He is a 51-year-old man who came to us with gradual symptoms such as shortness of breath and myalgia, with a history of smoking and coronavirus disease 2019, and in his computerized tomography scan, two views of halo sign and reverse halo sign were seen along with other lesions. In further investigations, due to his lack of recovery, a biopsy was prepared, and with a definitive diagnosis of lung adenocarcinoma, we treated the patient appropriately. Conclusion: When a patient presents with halo sign and reverse halo sign on computerized tomography scan and smokes, it is necessary to take a biopsy of the observed lesions to rule out primary lung carcinoma.

My notes (saved in your browser only)

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

europepmc
last seen: 2026-05-19T01:45:01.086888+00:00