Orfamide-A-mediated bacterial-algal interactions involve specific Ca2+ signalling pathways

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Abstract

The antagonistic bacterium Pseudomonas protegens secretes the cyclic lipopeptide orfamide A, which triggers a Ca 2+ signal, causing the deflagellation of the green microalga Chlamydomonas reinhardtii . By investigating targeted synthetic orfamide A variants and inhibitors, we found that at least two Ca 2+ -signalling pathways and TRP channels are involved in this response.

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europepmc
last seen: 2026-05-19T01:45:01.086888+00:00