Factors Associated with Correct Vaccination Among Children Aged 24 to 48 Months Hospitalized in National Hospitals of Bujumbura | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Factors Associated with Correct Vaccination Among Children Aged 24 to 48 Months Hospitalized in National Hospitals of Bujumbura Felix NIYONGABO, Laetitia Niyoyunguruza, Esperance Kabusoni, and 2 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-6486834/v1 This work is licensed under a CC BY 4.0 License Status: Posted Version 1 posted You are reading this latest preprint version Abstract Introduction : In Africa, although vaccines are often available free of charge in health facilities, many children evade various strategies put in place to reach them. In recent years, despite Burundi maintaining high coverage in all antigens (over 80% since the launch of the PEV in 1980), performance has begun to decline. From 2015 to 2017, all coverage rates experienced a slight regression, and the WHO/UNICEF figures for 2018 confirm this downward trend. The objective of this work is to contribute to the reduction of infant morbidity and mortality due to vaccinepreventable diseases by identifying factors associated with correct vaccination among children aged 24 to 48 months hospitalized in national hospitals in Bujumbura. Methodology : A cross-sectional analytical study was conducted in 4 national hospitals in Burundi. A sample of 216 children was selected, and the collected data were entered into Epinfo 7.2 software and transferred to Stata 15 for analysis. Three types of analyses were performed: descriptive analysis, univariate logistic regression, and multivariate logistic regression. After modeling, variables with a p-value <0.05 were considered associated with correct vaccination. Results : Out of 216 children, correct vaccination was observed in 64.81%. The average age of mothers was 29.4 ± 5.43 years, ranging from 15 to 45 years. Factors significantly associated with correct vaccination after modeling were: husband's level of education [OR = 15.41; P = 0.021], household income [OR = 10.23; P = 0.021], distance from residence to vaccination facility [OR = 0.12; P = 0.000], and mothers' knowledge levels of vaccine-preventable diseases [OR = 1.73; P = 0.004]. The model was well-calibrated (the p-value of the Lemeshow test is 0.6697) with a 90% capacity to correctly classify observations. Conclusion : The study's results indicate that children are not properly vaccinated despite the service being free. Various factors influencing correct vaccination status were identified, including the level of education of the head of the household, income level, distance to vaccination facilities, and mothers' knowledge of vaccine-preventable diseases. It is essential to implement interventions targeting these factors associated with correct vaccination to reduce morbidity and mortality from vaccine-preventable diseases. Epidemiology associated factors correct vaccination national hospitals children aged 24 to 48 months Full Text Additional Declarations The authors declare no competing interests. Cite Share Download PDF Status: Posted Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-6486834","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":445240718,"identity":"95d40ce1-372e-46a2-8b05-d985eb0ebb30","order_by":0,"name":"Felix NIYONGABO","email":"data:image/png;base64,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","orcid":"https://orcid.org/0000-0002-5805-4875","institution":"University of Burundi, Bujumbura, Burundi.","correspondingAuthor":true,"prefix":"","firstName":"Felix","middleName":"","lastName":"NIYONGABO","suffix":""},{"id":445240719,"identity":"e7cc1a20-4caa-4b17-88bf-69a6941ee127","order_by":1,"name":"Laetitia Niyoyunguruza","email":"","orcid":"","institution":"University of Burundi, Bujumbura, Burundi.","correspondingAuthor":false,"prefix":"","firstName":"Laetitia","middleName":"","lastName":"Niyoyunguruza","suffix":""},{"id":445240720,"identity":"6053adb8-c717-41f0-89b7-6d965cc148f6","order_by":2,"name":"Esperance Kabusoni","email":"","orcid":"","institution":"National Institute of Public Health, Bujumbura,Burundi","correspondingAuthor":false,"prefix":"","firstName":"Esperance","middleName":"","lastName":"Kabusoni","suffix":""},{"id":445240721,"identity":"b22d50aa-e4a1-424f-a660-98d9855956e2","order_by":3,"name":"Butoyi Jean Marie","email":"","orcid":"","institution":"University of Burundi, Bujumbura, Burundi.","correspondingAuthor":false,"prefix":"","firstName":"Butoyi","middleName":"Jean","lastName":"Marie","suffix":""},{"id":445240722,"identity":"75c57b2c-1e2b-4c5a-89ea-02a6bd71a8b3","order_by":4,"name":"Yves Coppieters","email":"","orcid":"","institution":"Université Libre de Bruxelles (ULB), Brussels, Belgium.","correspondingAuthor":false,"prefix":"","firstName":"Yves","middleName":"","lastName":"Coppieters","suffix":""}],"badges":[],"createdAt":"2025-04-19 23:49:44","currentVersionCode":1,"declarations":{"humanSubjects":false,"vertebrateSubjects":true,"conflictsOfInterestStatement":false,"humanSubjectEthicalGuidelines":false,"humanSubjectConsent":false,"humanSubjectClinicalTrial":false,"humanSubjectCaseReport":false,"vertebrateSubjectEthicalGuidelines":true},"doi":"10.21203/rs.3.rs-6486834/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-6486834/v1","draftVersion":[],"editorialEvents":[],"editorialNote":"","failedWorkflow":false,"files":[{"id":81071440,"identity":"f2d7f37e-7a57-4844-afae-b631035b6f2e","added_by":"auto","created_at":"2025-04-22 01:53:05","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":384484,"visible":true,"origin":"","legend":"","description":"","filename":"Manuscript.pdf","url":"https://assets-eu.researchsquare.com/files/rs-6486834/v1_covered_88d44cbb-37c8-4b43-bb91-9852a4d4a81c.pdf"}],"financialInterests":"The authors declare no competing interests.","formattedTitle":"\u003cp\u003eFactors Associated with Correct Vaccination Among Children Aged 24 to 48 Months Hospitalized in National Hospitals of Bujumbura\u003c/p\u003e","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":true,"highlight":"","institution":"Université du Burundi","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"
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