Evaluation of different antiandrogenic progestins on clinical and biochemical variables in polycystic ovary syndrome

In: The European Journal of Contraception & Reproductive Health Care · 2020 · vol. 25(3) , pp. 176–181 · doi:10.1080/13625187.2020.1736546 · PMID:32191532 · W3012491756
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AI-generated summary by claude@2026-06, 2026-06-10

Dienogest and drospirenone significantly increased SHBG, dehydroepiandrosterone sulfate, and total testosterone levels in PCOS patients, with dienogest having a stronger effect than cyproterone acetate.

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Abstract

Our study showed that DNG exerted an important stimulatory effect on SHBG concentrations, which was less than that of DRSP but greater than that of CMA. Similar results were also obtained for dehydroepiandrosterone sulphate and total testosterone.

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