Risk factors, diagnosis, prevention and treatment of endometriosis associated pain and cancers: An update

The observation that endometriosis is a cancer precursor has now been corroborated with the knowledge that mutations that are present in endometriosis-associated cancers can be found in contiguous endometriosis lesions. The diagnostic process of endometrial diseases from a clinical point of view is commonly suspected and for more accurate diagnosis Magnetic Resonance Imaging (MRI) or/and vaginal ultrasonography of the pelvis should be applied. The procedure of management of endometrial disorders is depended mainly on the initial presentation of the patient whether subfertility or pain is. The main aims of the treatments are including normal functional anatomy recovery, elimination of various kinds of cysts, endometriotic implants removal, symptomatic treatment, and decrement of disease development. Additionally, due to the influence of therapeutic conditions on life quality, the importance of applying personalized medicine should be considered. The main objective of the present study is to review available documents about the most proper procedures for the management of the endometrial disorder. In this way, the symptoms, risk factors including an increased risk of cancer, diagnosis, prevention, and treatment of this disorder are discussed.