High-intensity Focused Ultrasound is a Better Choice for Women with Fertility Desire: A Systematic Review and Meta-analysis of the Comparison between High-intensity Focused Ultrasound and Laparoscopic Treatment of Uterine Fibroids

Ying Hu, Xiaohong Song, Linjun Xu, Zhenfeng Zhou
Gynecology and minimally invasive therapy · 2023 · vol. 13(2) , pp. 79–89 · doi:10.4103/gmit.gmit_23_23 · PMID:38911304 · W4388085108
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⚙ AI-generated summary by claude@2026-06, 2026-06-07 ⓘ

High-intensity focused ultrasound (HIFU) treatment for uterine fibroids resulted in higher spontaneous pregnancy and delivery rates compared to laparoscopic myomectomy, though with potentially increased miscarriage rates.

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Abstract

High-intensity focused ultrasound (HIFU) is commonly used to treat uterine fibroids and adenomyosis, but there is no evidence using metadata to compare fertility outcomes between conventional laparoscopic procedures and HIFU. The purpose of this study analysis is that evidence-based fertility outcomes may provide better treatment options for clinicians and patients considering fertility. The literature on fertility data for HIFU surgery versus laparoscopic myomectomy was searched in seven English language databases from January 1, 2010, to November 23, 2022. A total of 1375 articles were received in the literature, 14 of which were selected. We found that women who underwent HIFU surgery had higher rates of spontaneous pregnancy, higher rates of spontaneous delivery, and higher rates of full-term delivery but may have higher rates of miscarriage or postpartum complications than women who underwent laparoscopic myomectomy. Looking forward to future studies, it is hoped that the literature will examine endometrial differences in women who undergo HIFU and laparoscopic myomectomy to demonstrate the ability of endometrial repair. The location of fibroids in the sample should also be counted to allow for attribution statistics on the cause of miscarriage.

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adenomyosis

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