A role of chronic endometritis is in development of different forms of hyperplastic processes of endometrium

In: Perinatology and reproductology: from research to practice · 2024 · vol. 4(1) , pp. 77–82 · doi:10.52705/2788-6190-2024-01-12 · W4406673501
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This study investigated clinical features of endometrial hyperplasia in perimenopausal women, finding that chronic endometritis correlates with earlier disease onset and longer duration.

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Abstract

The objective:to set the clinical features of different forms of hyperplastic processes of endometrium for women in a perimenopausal period taking into account the role of chronic endometritis.Materials and methods. It is conducted clinical-and-laboratory inspection 100 patients with the uterine bleeding of different character and presence of echographic signs of pathology of endometrium. After an inspection which included clinical-and-laboratory and echographic methods, the separate diagnostic scraping off of uterus was conducted all patients under control hysteroscopy. Depending on the results of histological research of scraping of the cervical canal and cavity of uterus complex immunohistochemical research after which five basic groups were formed for 20 patients in each was conducted: 1 group – women with simple hyperplasia of endometrium without atypia, 2 groups – complex hyperplasia of endometrium without atypia, 3 groups are hyperplasia of atypia, 4 groups are patients from hyperplastic processes of endometrium in combination with chronic endometritis, 5 group – women with chronic endometritis and reactive hyperplasia of endometrium. Results. For patients with combination of hyperplasia of endometrium and chronic endometritis and with reactive hyperplasia, as compared to hyperplasia without atypia and with atypia, more early beginning and expressed of clinical symptoms of disease, duration of which exceeds 2 years, is marked. For women from an outage and difficult typical and atypical hyperplasia connection between the morphological variant of pathological process and pathognomonic clinical symptoms stop out. In the structure of concomitant diseases for patients the inflammatory processes of organs of small pelvis prevail (as compared to hyperplasia without atypia and with atypia) with the presence of chronic endometritis, the of high quality diseases ofservix, hyperplastic processes of endometrium which testifies to the expressed system character of pathology.Conclusions. The got results must be taken into account at development of algorithm of diagnostic and treatment-and-prophylactic measures for women with the hyperplastic processes of endometrium, including, and on a background chronic endometritis. Keywords: chronic endometritis, hyperplastic processes of endometrium, clinic, diagnostics.

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