IRREVERSIBLE INHIBITORS OF TYROSINE KINAZES, PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND USE THEREOF

BRIDGES ALEXANDER JAMES, DENNY WILLIAM ALEXANDER, DOBRUSIN ELLEN MYRA, DOHERTY ANNETTE MARIAN, FRY DAVID W, MCNAMARA DENNIS JOSEPH, SHOWALTER HOWARD DANIEL HOLLIS, SMAILL JEFFREY B, ZHOU HAIRONG
2008
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Abstract

The invention relates to compounds represented by formula I: which are irreversible inhibitors of tyrosine kinazes, to pharmaceutiyal compositions containing the same and to the use thereof in the treatment of cancer, atherosclerosis, restenosis, endometriosis and psoriasis.

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europepmc
last seen: 2026-07-06T06:10:23.601157+00:00