Medication therapy of endometriosis: chances and prospects

М.Б. Хамошина, M. I. Vakhabova, Е. А. Калинина
In: Медицинский совет, Vol 0, Iss 8, Pp 23-27 (2013) · 2013 · doi:10.21518/2079-701x-2013-8-23-27 · W2736378478
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⚙ AI-generated summary by claude@2026-06, 2026-06-10 ⓘ

This paper discusses the varied pathogenesis and clinical presentations of endometriosis, advocating for combination therapy of surgery and individualized long-term medication based on patient age and reproductive goals.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-10 · read from full text ⓘ

The paper is a narrative discussion of medication therapy for endometriosis, framing the disease as common and heterogeneous in presentation and mechanism, with a chronic progressive course and major effects on physical, psychological, social, and reproductive well-being. It outlines that variability in clinical signs and lesion topography has led to multiple treatment algorithms and the need for an individualized approach. The key point is that many experts view endometriosis as a proliferative condition and therefore favor combined treatment, ideally involving surgical management plus long-term follow-up medication therapy tailored to patient age and reproductive plans, while noting no new experimental results are presented. This paper is centrally about endometriosis — it reviews the role of medication therapy and its integration with surgical and follow-up management for endometriosis.

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Abstract

Endometriosis is one of the most common women's diseases nowadays, commonly encountered by clinicians and researchers all over the world due to variability of assumed mechanisms of pathogenesis, a wide range of clinical manifestations (from asymptomatic forms to rather severe conditions), chronic progredient course, and particularly negative impact on physical condition, psychological status, social well-being and reproductive function of female patients [6, 11, 21, 23, 38]. Diversity of clinical signs and topography of the disease led to emergence of a wide range of treatment algorithms and necessitated the need for individual therapeutic approach [14, 22]. The majority of experts, while considering endometriosis to be a proliferative disease requiring surgical intervention to remove the spot, recognize combination treatment to be the method of choice. The method ideally provides for surgery (radical or organ-preserving) and long-term follow-up medication therapy taking into account the age and reproductive future of the patient [34, 42].
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Медицинский совет (Dec 2013) Medication therapy of endometriosis: chances and prospects Abstract Endometriosis is one of the most common women's diseases nowadays, commonly encountered by clinicians and researchers all over the world due to variability of assumed mechanisms of pathogenesis, a wide range of clinical manifestations (from asymptomatic forms to rather severe conditions), chronic progredient course, and particularly negative impact on physical condition, psychological status, social well-being and reproductive function of female patients [6, 11, 21, 23, 38]. Diversity of clinical signs and topography of the disease led to emergence of a wide range of treatment algorithms and necessitated the need for individual therapeutic approach [14, 22]. The majority of experts, while considering endometriosis to be a proliferative disease requiring surgical intervention to remove the spot, recognize combination treatment to be the method of choice. The method ideally provides for surgery (radical or organ-preserving) and long-term follow-up medication therapy taking into account the age and reproductive future of the patient [34, 42]. Keywords

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