Chronic pelvic pain and menorrhagia: Assessing treatment effectiveness

Part One: Chronic Pelvic PainChapter 2 reviews the current thinking and evidence base for diagnostic tests and medical, surgical and psychological therapies.Chapter 3 illustrates the situation regarding use of laparoscopic uterosacral nerve ablation (LUNA) in the UK, presenting the results of a survey of clinicians.Chapter 4 describes the protocol for the LUNA randomised controlled trial, detailing the outcomes, analytical methods and practicalities of the trial.Chapter 5 evaluates the clinical effectiveness of LUNA in alleviating chronic pelvic pain in a large randomised controlled trial.Chapter 6 describes the protocol for an individual patient data meta-analysis of five randomised LUNA trials.Chapter 7 presents results from the individual patient data meta-analysis, whereupon data from are subject to further subgroup analyses.