Use of a rapid hCG-beta-subunit radioimmunoassay in acute gynaecological emergencies

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A rapid radioimmunoassay for the beta-subunit of hCG diagnosed pregnancy in 22 of 24 women with lower abdominal pain and potential gynecological emergencies.

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Abstract

Chorionic gonadotrophin (hCG) was measured by a rapid and sensitive radioimmunoassay in 100 female patients with lower abdominal pain attending an emergency department. Of the 24 subjects with a positive result, 22 had evidence of pregnancy (ectopic or uterine). Of the 76 patients with negative results, 3 had some evidence of pregnancy. This test may be of considerable practical value in the differential diagnosis of acute abdominal emergencies in women of reproductive age.

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Condition tags

endometriosis

MeSH descriptors

Chorionic Gonadotropin Emergencies Genital Diseases, Female Pregnancy Tests, Immunologic Radioimmunoassay Abortion, Spontaneous Abortion, Spontaneous Acute Disease Adult Chorionic Gonadotropin Diagnosis, Differential Endometriosis Endometriosis Female Genital Diseases, Female Humans Ovarian Cysts Ovarian Cysts Pelvic Inflammatory Disease Pelvic Inflammatory Disease

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europepmc
last seen: 2026-09-06T09:34:12.023084+00:00
pubmed
last seen: 2026-05-13T22:10:10.897782+00:00
unpaywall
last seen: 2026-05-14T19:30:52.867331+00:00
License: public-domain-us · commercial use OK · attribution required
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