A prospective study of endometriosis and its outcome at tertiary care centre

Shilpa Ninama, Bijal D. Rami
In: International Journal of Reproduction, Contraception, Obstetrics and Gynecology · 2019 · vol. 8(12) , pp. 4847 · doi:10.18203/2320-1770.ijrcog20195332 · W2991045358
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⚙ AI-generated summary by claude@2026-06, 2026-06-08 ⓘ

This study examined clinical features and treatment outcomes for 100 endometriosis patients, finding that laparoscopy was diagnostic and therapeutic, with fulguration and oral contraceptives improving pregnancy rates and reducing pain symptoms.

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⚙ AI-generated deep summary by claude@2026-06, 2026-06-11 · read from full text ⓘ

This prospective study at a tertiary care teaching institute followed 100 patients with pelvic endometriosis over 3 years (2011–2013), classifying them by type and severity using the revised American Fertility Society system based on laparoscopic findings and clinical features. After one year of medical and surgical treatment, outcomes assessed included pregnancy rates and reductions in dysmenorrhoea and dyspareunia, with a reported 40 pregnancies, 60 patients with reduced dysmenorrhoea, and 20 with reduced dyspareunia. The paper reports that 76% presented with dysmenorrhoea, ovaries were the most common site affected (52%), and laparoscopy was performed in 86% of patients, with many treated via fulguration of endometriotic nodules and postoperative hormonal therapy. A key limitation explicitly implied by the design is the single-center, noncomparative prospective follow-up without a control group, which constrains attribution of outcomes to specific treatments. This paper is centrally about endometriosis — it prospectively evaluates clinical features, laparoscopic severity, and one-year outcomes after medical and surgical treatment in pelvic endometriosis.

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Abstract

Background: This study was conducted to detect various presenting clinical features, type and severity of pelvic endometriosis according to revised American fertility society classification. Objective of this study was to assess outcome of endometriosis after medical and surgical treatment in form of pregnancy, reduction of symptoms like dysmenorrhoea, dyspareunia and others.Methods: This prospective study conducted at one of tertiary care teaching institutes for period of 3 years from January 2011 to December 2013. A total number of 100 patients of pelvic endometriosis were examined and divided according to Revised American Fertility Society Classification on bases of severity, type and clinical features and laparoscopic findings. After 1 year of follow up, outcome assessed after completion of medical and surgical treatment in form of pregnancy, reduction of dysmenorrhoea and dyspareunia and other symptoms.Results: This study showed most affected patients (46%) belongs to 26-30 years of age group, dysmenorrhoea was the most common presenting symptoms in 76% patients. Most common site affected (52%) was ovaries. Laparoscopy was done in 86% patients. Most patients (44%) were benefited with fulguration of endometriotic nodules. 62% of patients were given oral contraceptive pills or progesterone pills after definitive surgery as freely available in Governmental setup and fewer side effects as compared to Danazol and GnRH analogues. 40 patients became pregnant after medical and surgical treatment, where 60 patients had reduced dysmenorrhoea and 20 patients had reduced dyspareunia.Conclusions: Laparoscopy is gold standard diagnostic as well as therapeutic tool in pelvic endometriosis as it can rule out other causes of infertility without interfering normal anatomy.
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Background

This study was conducted to detect various presenting clinical features, type and severity of pelvic endometriosis according to revised American fertility society classification. Objective of this study was to assess outcome of endometriosis after medical and surgical treatment in form of pregnancy, reduction of symptoms like dysmenorrhoea, dyspareunia and others.

Methods

This prospective study conducted at one of tertiary care teaching institutes for period of 3 years from January 2011 to December 2013. A total number of 100 patients of pelvic endometriosis were examined and divided according to Revised American Fertility Society Classification on bases of severity, type and clinical features and laparoscopic findings. After 1 year of follow up, outcome assessed after completion of medical and surgical treatment in form of pregnancy, reduction of dysmenorrhoea and dyspareunia and other symptoms.

Results

This study showed most affected patients (46%) belongs to 26-30 years of age group, dysmenorrhoea was the most common presenting symptoms in 76% patients. Most common site affected (52%) was ovaries. Laparoscopy was done in 86% patients. Most patients (44%) were benefited with fulguration of endometriotic nodules. 62% of patients were given oral contraceptive pills or progesterone pills after definitive surgery as freely available in Governmental setup and fewer side effects as compared to Danazol and GnRH analogues. 40 patients became pregnant after medical and surgical treatment, where 60 patients had reduced dysmenorrhoea and 20 patients had reduced dyspareunia.

Conclusions

Laparoscopy is gold standard diagnostic as well as therapeutic tool in pelvic endometriosis as it can rule out other causes of infertility without interfering normal anatomy. Metrics

References

Fauser BCJM, Diedrich K, Bouchard P, Domínguez F, Matzuk M, Franks S, et al. Contemporary genetic technologies and female reproduction. Human Repro Update. 2011;17(6):829-47. Painter JN, Anderson CA, Nyholt DR, Macgregor S, Lin J, Lee SH, et al. Genome-wide association study identifies a locus at 7p15. 2 associated with endometriosis. Nature Genet. 2011;43(1):51-4. Buyalos RP, Agarwal SK. Endometriosis-associated infertility. Cur Opin Obstet Gynecol 2000;12(5):377-81. Sinaii N, Cleary SD, Ballweg ML, Nieman LK, Stratton P. High rates of autoimmune and endocrine disorders, fibromyalgia, chronic fatigue syndrome and atopic diseases among women with endometriosis: a survey analysis. Human Repro. 2002;17(10):2715-24. Vercellini P, Trespidi L, De Giorgi O, Cortesi I, Parazzini F, Crosignani PG. Endometriosis and pelvic pain: relation to disease stage and localization. Fert Ster. 1996;65(2):299-304. Shah P, Adlakha A, Laproscopy management of moderate: Severe Endometriosis. J Minimal Access Surg. 2014 Jan-Mar;10(1):27-33. Fuchs F, Raunal P, Salama S, Guillot E, Le Tohic A, Chis C, et al. Reproductive Outcome after Laproscopic treatment of endometriosis in infertile Population. J Gynecol Obstet Biol Reprod (Paris). 2007;36:354-9. Capellino S, Montagna P, Villaggio B. Role of estrogens in inflammatory response: expression of estrogen receptors in peritoneal fluid macrophages from endometriosis. Ann New York Acad Sci. 2006;1069:263-7. Treloar SA, Wicks J, Nyholt DR, Montgomery GW, Bahlo M, Smith V, et al. Genomewide linkage study in 1,176 affected sister pair families identifies a significant susceptibility locus for endometriosis on chromosome 10q26. Am J Human Genet. 2005;77(3):365-76.

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Condition tags

endometriosisdysmenorrheadyspareuniainfertility

Citation neighborhood

Papers in the corpus that this work cites (lower rings, blue) and that cite this one (upper rings, green). Dot size scales with the paper's in-corpus citation count — bigger dot = more influential within the endo/adeno field. Click a dot to open that paper. [ expand to 2 hops ] — adds papers reached through this work's immediate citers/citees. Heavier; up to 60 extra dots.

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