Study on prolonged administration interval of triptorelin for post-operative endometriosis

Objective To evaluate the feasibility of prolonged administration interval of triptorelin for post-operative endometriosis. Methods 89 women with stage 3-4 endometriosis were randomly assigned to a study group (42 cases) and a control group (47 cases). The observation group were intramuscularly injected 3.75 mg triptorelin every 5 weeks after operation, and the control group every 4 weeks. Results During the treatment, there was no statistical difference in estrogen level between these two groups. The menstruation recovery time was (234.0±17.1) days in study group, and was (209.0±13.6) days in control group. Conclusions The injection of triptorelin every 5 weeks after operation for patients with stage 3-4 endometriosis is feasible. Key words: Endometriosis; Ovarian chocolate cyst; Gonadotropin-releasing hormone agonist; Triptorelin