Tubal endometriosis as an insidious risk factor for tubal implantation in a procedure of assisted reproductive technique

In: \n Volume: 33, Issue: 2\n 248-252\n \n · 2011 · vol. 33(2) , pp. 248–252 · doi:10.7197/cmj.v33i2.1008000796 · W1830435825
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This case report details bilateral tubal ectopic pregnancies in an IVF-ET patient with tubal endometriosis, suggesting implants on the tubal mucosa may facilitate implantation.

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Abstract

AbstractEndometriosis is often associated with female infertility and exhibits a massive impairment in the physiology of uterine contractility that interferes with sperm and/or embryo movements. We present an unusual case of bilateral tubal pregnancy during an Invitro Fertilization-Embryo Transfer (IVF-ET) procedure in a tubal endometriosis patient. Bilateral tubal ampullary ectopic pregnancies, 20-30 milimeters in diameter were diagnosed during laparoscopic examination and bilateral salpingectomy was performed. Endometriotic implants were detected pathologically on mucosal surfaces of both tubes demonstrating the possible deleterious effect of endometriosis on embryo movement. Tubal mucosal environment containing endometriotic implants may behave like original uterine endometrium for ectopic tubal implantation of transferred embryos. However, we think that in order to decrease the probability for tubal implantation of transferred embryos; consideration of bilateral tubal closure or salpingectomy for patients with endometriosis before proceeding to an IVF-ET procedure may be useful.Keywords: Pregnancy, ectopic, endometriosis, embryo transfer ÖzetEndometriozis çoğunlukla kadın infertilitesi ile ilişkilidir ve sperm ve/veya embriyo hareketlerini engelleyici, uterus kasılma fizyolojisinde belirgin bir bozulma ile kendini gösterir. Bir ender olgu olarak, İnvitro Fertilizasyon Embriyo Transferi (İVF-ET) prosedürü sırasında, bir tubal endometriozis hastasında bilateral tubal gebeliği sunduk. Laparoskopik değerlendirmede, 20-30 milimetre çapında bilateral tubal ampullada ektopik gebelik teşhis edildi ve bilateral salpenjektomi gerçekleştirildi. Endometriozisin, embriyo hareketini olası geciktirici etkisini gösteren, endometriyotik implantlar her iki tüpün mukozal yüzeylerinde patolojik olarak saptandı. Endometriyotik implantların oluşturduğu tubal mukozal ortam, transfer edilen embriyoların ektopik tubal implantasyonu için orijinal uterus endometriyumu gibi davranır. Bununla birlikte, biz, bir İVF-ET prosedürüne geçmeden önce, transfer edilen embriyoların tubal implantasyonu olasılığını azaltmak için, endometriozisli hastalara bilateral tubal kapama veya salpenjektomi uygulamasının göz önünde tutulmasının yararlı olabileceğini düşünmekteyiz.Anahtar sözcükler: Gebelik, ektopik, endometriozis, embriyo transfer

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endometriosisinfertility

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