Nonsteroidal anti-inflammatory drugs for management of pelvic pain in women

In: Medical Council · 2019 · pp. 27–33 · doi:10.21518/2079-701x-2019-7-27-32 · W2943854581
article OA: diamond CC0
AI-generated summary by claude@2026-06, 2026-06-09

Nonsteroidal anti-inflammatory drugs are pathogenetically substantiated for managing pelvic pain by reducing prostaglandins, aiding treatment of acute pelvic infections and idiopathic menstrual pain.

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AI-generated deep summary by claude@2026-06, 2026-06-09

The paper reviews evidence on the use of nonsteroidal anti-inflammatory drugs (NSAIDs) for managing pelvic pain in women, drawing on prior studies and clinical guideline information across gynecologic pain conditions. It summarizes that NSAIDs are commonly used for primary dysmenorrhea and discusses the broader inflammatory and pain mechanisms that can underlie pelvic pain, while also referencing an existing Cochrane review specifically on NSAIDs for endometriosis-related pain. The authors’ main limitation is that this is a narrative review that synthesizes heterogeneous sources rather than presenting new original data, so the conclusions depend on the quality and scope of the included literature. Relevance to endometriosis: it explicitly cites and discusses prior evidence from a Cochrane review of “Nonsteroidal anti-inflammatory drugs for pain in women with endometriosis,” though the paper’s main focus is NSAID use for pelvic pain in women more broadly.

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Abstract

Pelvic pain is one of the common causes for visiting a doctor, which can be the main symptom of gynecological diseases and an independent pathological condition. Acute pelvic pain is most often caused by an infection that affects the organs of a woman’s reproductive system. Non-infectious causes of pain are also associated with inflammation, and estrogens support pain and inflammation in women, which increases the risk of chronic pelvic pain (CPP). The urgency of the pelvic pain problem is considered not only in connection with an adequate diagnosis of its causes, but also from the perspective of managing the pain symptoms themselves. The anaesthesia strategy significantly improves the quality of life and prevents the development of chronic inflammatory diseases and CPP syndrome. Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used in pain therapy, and their effect consists in reducing the synthesis of prostaglandins and is pathogenetically substantiated both in the complex treatment of acute pelvic infections and in the treatment of idiopathic menstrual pain. The article presents clinical observations of the use of NSAIDs with the specified purpose.

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Condition tags

chronic_pelvic_pain

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References (21)

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last seen: 2026-06-10T17:14:06.276822+00:00
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