1-6-Substituted (3R,6R)-3-(2,3-Dihydro-1H-Inden-2-Yl)-2,5-Piperazinedione Derivatives as Oxytocin Receptor Antagonists For the Treatment of Preterm Labour, Dysmenorrhea and Endometriosis

LEACH COLIN ANDREW; LIDDLE JOHN; PEACE SIMON; PHILP JOANNE; SMITH IAN EDWARD DAVID; TERRELL LAMONT ROSCOE; ZHANG JING

1-6-Substituted (3R,6R)-3-(2,3-Dihydro-1H-Inden-2-Yl)-2,5-Piperazinedione Derivatives as Oxytocin Receptor Antagonists For the Treatment of Preterm Labour, Dysmenorrhea and Endometriosis

LEACH COLIN ANDREW, LIDDLE JOHN, PEACE SIMON, PHILP JOANNE, SMITH IAN EDWARD DAVID, TERRELL LAMONT ROSCOE, ZHANG JING

2008

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⚙ AI-generated summary by qwen3.7-flash, 2026-09-14 ⓘ

This patent describes Compound S, a 1-6-substituted piperazinedione derivative designed as an oxytocin receptor antagonist for treating endometriosis, dysmenorrhea, and preterm labor.

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Abstract

The present invention relates to Compound S of Formula (I).

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europepmc: last seen: 2026-07-28T06:14:09.330459+00:00