Effect of the Human Heart Material Uniformity on Modeling of the Body Surface Potential Map

This study investigates the influence of cardiac tissue uniformity on the accuracy of the Body Surface Potential Map (BSPM) generated from human heart simulations. A realistically shaped human torso was modeled using CT scan data, and the heart was reconstructed both as a volume matrix and a boundary surface. Two excitation propagation models were employed: the original Monodomain Reaction-Diffusion Equation (MD-RDE), assuming uniform conductivity, and a modified version accounting for non-uniform material properties. Comparative analysis of activation isochrones and BSPMs revealed slight differences, particularly during the QRS complex, although the overall impact of uniformity on BSPM accuracy was found to be minimal. These results suggest that while local differences exist, uniform and non-uniform models produce largely comparable BSPM results for many clinical and research purposes.