Percutaneous cryoablation of symptomatic abdominal scar endometrioma: initial reports

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Percutaneous cryoablation of symptomatic abdominal scar endometrioma in four patients demonstrated significant lesion volume decrease and pain reduction with promising short-term local control.

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This preliminary study reported short-term local control of percutaneous image-guided cryoablation for localized symptomatic abdominal scar endometrioma in four consecutive patients with 10 lesions, using a single-session procedure under general anesthesia and assessing pain and MRI response. Mean preoperative pain was 7 on a visual analog scale, and post-procedure superficial edema resolved within 2 weeks for all patients. At 6 months, mean postoperative pain decreased to 1.7, and MRI showed a significant volume decrease in all patients (72.2–100%; p = 0.028), with no severe complications reported (CTCAE grade >2). The main limitation is the very small, short-term, noncomparative “initial reports” design. This paper is centrally about endometriosis — it specifically evaluates percutaneous cryoablation for symptomatic abdominal scar endometriomas.

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Abstract

PURPOSE: The purpose of this preliminary study was to report the short-term local control of percutaneous image-guided cryoablation of localized symptomatic abdominal scar endometrioma. METHODS: Four consecutive patients (mean age 34.5 years) with a total of ten lesions were included, with mean preoperative pain of 7 (range 5-9) on the visual analog scale. Cryoablation was performed in a single session under general anesthesia. RESULTS: Postoperative superficial edema disappeared within 2 weeks for all patients. No severe complications (>grade 2 according to the CTCAE classification) were reported. Mean postoperative pain was 1.7 at 6 months (range 0-5) and magnetic resonance imaging demonstrated a significant volume decrease for all patients (range 72.2-100%; p = 0.028). CONCLUSIONS: Percutaneous cryoablation shows promising local control in patients with symptomatic abdominal wall endometriosis.
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Abstract

Purpose The purpose of this preliminary study was to report the short-term local control of percutaneous image-guided cryoablation of localized symptomatic abdominal scar endometrioma.

Methods

Four consecutive patients (mean age 34.5 years) with a total of ten lesions were included, with mean preoperative pain of 7 (range 5–9) on the visual analog scale. Cryoablation was performed in a single session under general anesthesia.

Results

Postoperative superficial edema disappeared within 2 weeks for all patients. No severe complications (>grade 2 according to the CTCAE classification) were reported. Mean postoperative pain was 1.7 at 6 months (range 0–5) and magnetic resonance imaging demonstrated a significant volume decrease for all patients (range 72.2–100 %; p = 0.028).

Conclusions

Percutaneous cryoablation shows promising local control in patients with symptomatic abdominal wall endometriosis. Similar content being viewed by others

References

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Condition tags

endometriosisendometrioma

MeSH descriptors

Abdominal Wall Cicatrix Cryosurgery Endometriosis Abdominal Wall Adult Cicatrix Cryosurgery Endometriosis Female Humans Magnetic Resonance Imaging Pain Measurement Postoperative Pain Prospective Studies Treatment Outcome

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