The deficiency of hereditary protein C caused arterial thrombosis of the extremities and myocardial infarction in one case

We report a patient with both arterial thrombosis of the extremities and myocardial infarction. There was no obvious cardiac vascular stenosis after coronary computed tomography angiography examination, and the patient's myocardial infarction was considered to be caused by coronary artery embolism. Genetic testing confirmed that the patient had inherited protein C deficiency. After lifelong anticoagulant therapy with rivaroxaban, no further arteriovenous thrombosis events occurred. We propose that for patients with multiple arterial thrombosis or myocardial infarction patients without obvious risk factors of coronary heart disease, inherited or acquired thrombophilia should be screened according to the individual condition of the patient, which is beneficial to the etiological diagnosis, treatment and prevention of adverse events.