Mood Swing during Menstruation: Confounding Factors and Drug Use

other OA: gold CC-BY-NC-ND-4.0
📄 Open PDF View on PubMed View at publisher

Abstract

BACKGROUND: Premenstrual syndrome (PMS) is a physiologic process in women where mood swing is one of the symptoms influencing the psycho-emotional, physical, and behavioral reactions exhibited by women during menstruation. This study elucidates the effect of mood swing, confounding factors and healthcare-seeking behaviors of women in an educational environment. METHODS: Exactly 328 women who were within reproductive ages 16 and 35 years participated in this study. A survey method was adopted; validated and standardized questionnaires were administered to confidentially assess the effect of mood swing via PMS. All data were analyzed with SPSS 25.0; descriptive method was adopted and results were expressed in percentages. RESULTS: Mood swing was discovered as a symptom overlapping with psycho-emotional, physical, and behavioral symptoms during menstruation. The overall PMS prevalence was 67.4% while PMDD prevalence was 25.6%. Psycho-emotional symptoms: anger, irritability, depression. Physical symptoms: coldness, paleness, food craving, breast tenderness, digestive changes. Behavioral symptoms: social withdrawal, nocturnal social activity, absenteeism, poor work or academic performance, increased libido. Confounding factors include stress, gynecological conditions such as endometriosis, uterine fibroid, ovarian cyst, pelvic adhesion, and polycystic ovarian syndrome. Also, 22.9% had a family history of bipolar disorder (BD) while 30.2% had previous diagnosis. Severe pain was a major factor for seeking treatment; Paracetamol, and Piroxicam were frequently used drugs. CONCLUSIONS: Severe PMS triggers mood swing and can badly affect academic or work activities; victims either endure the pain due to socio-cultural and financial factors or take unsuitable medications where abuse is inevitable.

My notes (saved in your browser only)

Condition tags

endometriosis

MeSH descriptors

Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome Premenstrual Syndrome

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. The paper's references may be in our DB but unresolved to ``paper_id`` (resolution happens at ingest when the cited DOI matches a row we already have). Run the cross-source citation reconcile pass to retry.

Source provenance

europepmc
last seen: 2026-07-08T06:14:57.058073+00:00
pubmed
last seen: 2026-07-08T06:14:46.351802+00:00
unpaywall
last seen: 2026-05-14T19:30:52.867331+00:00
License: CC-BY-NC-ND-4.0 · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine