Poor Ovarian Response with High Cancellation Rate during Controlled Ovarian Hyperstimulation after Enucleation of Ovarian Endometriomas

Robert Kuo‐Kuang Lee, Hsin‐Yi Ho, Shing‐Jyh Chang, Tseng-Kai Lin, Jin-Tsung Su, Yuh‐Ming Hwu, Ming-Huei Lin
In: Taiwanese Journal of Obstetrics and Gynecology · 2003 · vol. 42(2) , pp. 85–90 · doi:10.29787/tjog.200306.0001 · W2223383328
article OA: closed CC0 ⤵ 2 in-corpus citations
Full text JSON View on OpenAlex View at publisher
⚙ AI-generated summary by claude@2026-06, 2026-06-09 ⓘ

Patients undergoing IVF after surgical removal of ovarian endometriomas showed significantly higher cancellation rates and poorer ovarian response during controlled ovarian hyperstimulation compared to controls.

One-sentence paraphrase of the abstract; not a substitute for reading it. No clinical advice. How this works

⚙ AI-generated deep summary by claude@2026-06, 2026-06-09 · read from full text ⓘ

This retrospective study compared ovarian response during controlled ovarian hyperstimulation (COH) for IVF in 51 patients (71 cycles) who previously underwent cystectomy for ovarian endometriomas versus 48 male-factor infertility controls (52 cycles) treated with ICSI. The key findings were that the endometrioma-surgery group had a significantly higher cancellation rate (28.2% vs 7.7%) and showed lower estradiol levels and fewer dominant follicles on the hCG day, fewer mature oocytes retrieved, and fewer embryos available. Despite these differences in ovarian response, clinical pregnancy rate, implantation rate, and live birth rate were not statistically different between groups. The paper’s main limitation is its retrospective design using medical records across a long period (1992–1999). This paper is centrally about endometriosis—specifically how prior surgical enucleation of ovarian endometriomas affects ovarian response and cancellation rates during COH for IVF.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

Objective: To evaluate ovarian response during controlled ovarian hyperstimulation (COH) in patients with endometriomas previously treated surgically. Material(s) and Method(s): The medical records of patients under 40 years old undergoing IVF from January 1992 to December 1999 were retrospectively reviewed. In group 1 (51 patients, 71 cycles), all patients had undergone cystectomy for ovarian endometriomas prior to IVE. A control group 2 (48 patients, 52 cycles) had had male factor infertility and had undergone ICSI. The ovarian response and cancellation rates of these two groups during COH were compared. Result(s): The cancellation rate in group 1 was significantly higher than in group 2 (28.2% vs. 7.7%, P＜0.05). The estradiol level and number of dominant follicles on the day of hCG injection, the number of mature oocytes retrieved, and the number of embryos available were all significantly lower in group 1. There were no statistical differences in the clinical pregnancy rate (32.0% vs. 42.6%), implantation rate (13.1% vs. 15.1%) or live birth rate (30.0% vs. 31.9%). Conclusion(s): Ovarian surgery may damage ovarian reserve, resulting in poor ovarian response and increased cancellation rate during COH.
Full text 2,452 characters · extracted from oa-doi-fallback · 2 sections · click to expand

Objective

To evaluate ovarian response during controlled ovarian hyperstimulation (COH) in patients with endometriomas previously treated surgically. Material(s) and Method(s): The medical records of patients under 40 years old undergoing IVF from January 1992 to December 1999 were retrospectively reviewed. In group 1 (51 patients, 71 cycles), all patients had undergone cystectomy for ovarian endometriomas prior to IVE. A control group 2 (48 patients, 52 cycles) had had male factor infertility and had undergone ICSI. The ovarian response and cancellation rates of these two groups during COH were compared. Result(s): The cancellation rate in group 1 was significantly higher than in group 2 (28.2% vs. 7.7%, P＜0.05). The estradiol level and number of dominant follicles on the day of hCG injection, the number of mature oocytes retrieved, and the number of embryos available were all significantly lower in group 1. There were no statistical differences in the clinical pregnancy rate (32.0% vs. 42.6%), implantation rate (13.1% vs. 15.1%) or live birth rate (30.0% vs. 31.9%). Conclusion(s): Ovarian surgery may damage ovarian reserve, resulting in poor ovarian response and increased cancellation rate during COH.

Objective

To evaluate ovarian response during controlled ovarian hyperstimulation (COH) in patients with endometriomas previously treated surgically. Material(s) and Method(s): The medical records of patients under 40 years old undergoing IVF from January 1992 to December 1999 were retrospectively reviewed. In group 1 (51 patients, 71 cycles), all patients had undergone cystectomy for ovarian endometriomas prior to IVE. A control group 2 (48 patients, 52 cycles) had had male factor infertility and had undergone ICSI. The ovarian response and cancellation rates of these two groups during COH were compared. Result(s): The cancellation rate in group 1 was significantly higher than in group 2 (28.2% vs. 7.7%, P＜0.05). The estradiol level and number of dominant follicles on the day of hCG injection, the number of mature oocytes retrieved, and the number of embryos available were all significantly lower in group 1. There were no statistical differences in the clinical pregnancy rate (32.0% vs. 42.6%), implantation rate (13.1% vs. 15.1%) or live birth rate (30.0% vs. 31.9%). Conclusion(s): Ovarian surgery may damage ovarian reserve, resulting in poor ovarian response and increased cancellation rate during COH.

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

⚙ Ask this paper AI returns verbatim quotes from the full text · source: oa-doi-fallback ⓘ

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Condition tags

infertility

Citation neighborhood (sparse)

Too few in-corpus citations on either side for a chart; here are the lists.

Cited by (2)

Cited by (2)

Source provenance

openalex
last seen: 2026-06-10T17:14:06.276822+00:00
License: CC0 · commercial use OK