Bilateral breast cancer in a 65-year-old man | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Bilateral breast cancer in a 65-year-old man Arman Sharbatdaran, Mohammed Twam, Hosseine Ghorbane, Novin Nikbakhsh This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-567335/v1 This work is licensed under a CC BY 4.0 License Status: Published Journal Publication published 01 Jan, 2022 Read the published version in Archives of Clinical and Medical Case Reports → Version 1 posted You are reading this latest preprint version Abstract Globally, breast cancer in men is exceedingly uncommon. The misinterpretation of signs and symptoms and lack of a proper medical history can lead to the progression of rare conditions to advanced stages. We report the case of a 65-year-old man who presented to the clinic complaining about progressive bilateral dull breast pain. He had been diagnosed with bilateral grade II invasive ductal carcinoma three months prior, and he underwent bilateral mastectomy followed by chemotherapy as a part of his treatment plan. Cancer Biology Male breast cancer Pathology Radiology Bilateral physical exam History of presenting illness Figures Figure 1 Figure 2 Full Text Cite Share Download PDF Status: Published Journal Publication published 01 Jan, 2022 Read the published version in Archives of Clinical and Medical Case Reports → Version 1 posted You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-567335","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":30594404,"identity":"b5a1b699-ffc2-410a-a38e-01b35da02a81","order_by":0,"name":"Arman Sharbatdaran","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA1ElEQVRIiWNgGAWjYPCCAzxs7A1A2sCCeC1y/DwHQFokiNdiLDkjAcQgQgv/7NOJnwv+3EnccPP51Q0/CiQY+Nu7E/BqkTiXu1l6ZtuzxA23c8pu9gAdJnHm7Ab81pzh3SDN23AYpCXtBg9Qi4FELn4t8md4N//m+QPUcvNM2s0/xGgxOMO7TZqH7TDQ++zHbhNliyFQizVv22FgIOew3ZYxkOAh6Bc5oMNuAx0GjMrjz26++WMjx9/eS8D7CMBjACaJVQ4C7A9IUT0KRsEoGAUjCAAAV5lLakCrkhUAAAAASUVORK5CYII=","orcid":"https://orcid.org/0000-0002-7097-0032","institution":"St. George’s University School of Medicine, Grenada","correspondingAuthor":true,"submittingAuthor":false,"prefix":"","firstName":"Arman","middleName":"","lastName":"Sharbatdaran","suffix":""},{"id":30594405,"identity":"b6b8894c-7809-48df-bb66-6dda847b5702","order_by":1,"name":"Mohammed Twam","email":"","orcid":"","institution":"St. George’s University School of Medicine, Grenada","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Mohammed","middleName":"","lastName":"Twam","suffix":""},{"id":30594406,"identity":"6a340330-edfe-4bd7-8e4f-537bd4d26297","order_by":2,"name":"Hosseine Ghorbane","email":"","orcid":"","institution":"Babol University of Medical Sciences, Babol, Iran","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Hosseine","middleName":"","lastName":"Ghorbane","suffix":""},{"id":30594407,"identity":"d30b252c-ea6d-438e-8f93-0d223282dfa8","order_by":3,"name":"Novin Nikbakhsh","email":"","orcid":"","institution":"Babol University of Medical Sciences, Babol, Iran","correspondingAuthor":false,"submittingAuthor":false,"prefix":"","firstName":"Novin","middleName":"","lastName":"Nikbakhsh","suffix":""}],"badges":[],"createdAt":"2021-05-27 12:14:33","currentVersionCode":1,"declarations":"","doi":"10.21203/rs.3.rs-567335/v1","doiUrl":"https://doi.org/10.21203/rs.3.rs-567335/v1","draftVersion":[],"editorialEvents":[{"content":"https://doi.org/10.26502/acmcr.96550458","type":"published","date":"2022-01-01T10:23:31+00:00"}],"editorialNote":"","failedWorkflow":false,"files":[{"id":9898282,"identity":"d161c7a6-a85d-4579-9b71-07df896a97c2","added_by":"auto","created_at":"2021-06-02 16:46:14","extension":"jpg","order_by":1,"title":"Figure 1","display":"","copyAsset":false,"role":"figure","size":92901,"visible":true,"origin":"","legend":"Figure 1 caption not available with this version","description":"","filename":"f1.jpg","url":"https://assets-eu.researchsquare.com/files/rs-567335/v1/ef02326b099f14203eec30ce.jpg"},{"id":9898517,"identity":"a59c7953-d455-49f7-8edc-6f1a5c38becc","added_by":"auto","created_at":"2021-06-02 16:49:14","extension":"jpg","order_by":2,"title":"Figure 2","display":"","copyAsset":false,"role":"figure","size":64347,"visible":true,"origin":"","legend":"Figure 2 caption not available with this version","description":"","filename":"f2.jpg","url":"https://assets-eu.researchsquare.com/files/rs-567335/v1/f94d4fd38c3c3e4244a45396.jpg"},{"id":18656134,"identity":"07c28e88-789a-4e64-8de1-6ec71cd49f5b","added_by":"auto","created_at":"2022-02-27 10:23:42","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":549423,"visible":true,"origin":"","legend":"","description":"","filename":"FINALCASEREPORTBILATERALBREASTCANCER.pdf","url":"https://assets-eu.researchsquare.com/files/rs-567335/v1_covered.pdf"},{"id":13639537,"identity":"1674360b-b6e0-47b2-b58c-1de5f371f151","added_by":"auto","created_at":"2021-09-17 08:56:09","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":544300,"visible":true,"origin":"","legend":"","description":"","filename":"FINALCASEREPORTBILATERALBREASTCANCER.pdf","url":"https://assets-eu.researchsquare.com/files/rs-567335/v1_covered.pdf"},{"id":10605521,"identity":"4dc5e4a0-b22e-421e-bc35-c699aabede6d","added_by":"auto","created_at":"2021-06-21 15:41:03","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":540722,"visible":true,"origin":"","legend":"","description":"","filename":"FINALCASEREPORTBILATERALBREASTCANCER.pdf","url":"https://assets-eu.researchsquare.com/files/rs-567335/v1_covered.pdf"},{"id":10392915,"identity":"b87e9b92-29ae-4fdd-89c9-18a35fc0d330","added_by":"auto","created_at":"2021-06-15 15:23:35","extension":"pdf","order_by":1,"title":"","display":"","copyAsset":false,"role":"manuscript-pdf","size":540683,"visible":true,"origin":"","legend":"","description":"","filename":"FINALCASEREPORTBILATERALBREASTCANCER.pdf","url":"https://assets-eu.researchsquare.com/files/rs-567335/v1_covered.pdf.old"}],"financialInterests":"","formattedTitle":"Bilateral breast cancer in a 65-year-old man","fulltext":[{"header":"Full Text","content":"This preprint is available for \u003ca href='/article/rs-567335/latest.pdf' target='_blank'\u003edownload as a PDF\u003c/a\u003e."}],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":true,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":true,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":false,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"
[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true},"keywords":"Male breast cancer, Pathology, Radiology, Bilateral, physical exam, History of presenting illness","lastPublishedDoi":"10.21203/rs.3.rs-567335/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-567335/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"Globally, breast cancer in men is exceedingly uncommon. The misinterpretation of signs and symptoms and lack of a proper medical history can lead to the progression of rare conditions to advanced stages. We report the case of a 65-year-old man who presented to the clinic complaining about progressive bilateral dull breast pain. He had been diagnosed with bilateral grade II invasive ductal carcinoma three months prior, and he underwent bilateral mastectomy followed by chemotherapy as a part of his treatment plan.","manuscriptTitle":"Bilateral breast cancer in a 65-year-old man","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2021-06-02 16:46:12","doi":"10.21203/rs.3.rs-567335/v1","editorialEvents":[{"type":"communityComments","content":0}],"status":"published","journal":{"display":true,"email":"
[email protected]","identity":"researchsquare","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":true,"externalIdentity":"","sideBox":"","snPcode":"","submissionUrl":"/submission","title":"Research Square","twitterHandle":"researchsquare","acdcEnabled":true,"dfaEnabled":false,"editorialSystem":"","reportingPortfolio":"","inReviewEnabled":false,"inReviewRevisionsEnabled":true}}],"origin":"","ownerIdentity":"3a87dddc-7e51-47af-b521-2859be56365a","owner":[],"postedDate":"June 2nd, 2021","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"published-in-journal","subjectAreas":[{"id":4752018,"name":"Cancer Biology"}],"tags":[],"updatedAt":"2022-02-27T10:23:31+00:00","versionOfRecord":{"articleIdentity":"rs-567335","link":"https://doi.org/10.26502/acmcr.96550458","journal":{"identity":"archives-of-clinical-and-medical-case-reports","isVorOnly":true,"title":"Archives of Clinical and Medical Case Reports"},"publishedOn":"2022-01-01 10:23:31","publishedOnDateReadable":"January 1st, 2022"},"versionCreatedAt":"2021-06-02 16:46:12","video":"","vorDoi":"10.26502/acmcr.96550458","vorDoiUrl":"https://doi.org/10.26502/acmcr.96550458","workflowStages":[]},"version":"v1","identity":"rs-567335","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-567335","identity":"rs-567335","version":["v1"]},"buildId":"7rjqhiLT3MXkJMwkYKINL","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}
Text is read by the "Ask this paper" AI Q&A widget below.
Extraction quality varies by source — PMC NXML preserves structure
cleanly, OA-HTML may include some navigation residue, and OA-PDF can
have broken hyphenation. The publisher copy
(via DOI)
is the canonical version.