Profiles (M1, M2) in Cases of Endometriosis

Objective: To determine the presence of an L-selectin gene P213S polymorphism in association with the pathogenesis of endometriosis.Design: Comparative analytical study using a 2 population case-control design.Setting: Department of Obstetrics and Gynaecology at Haji Adam Malik General Hospital, Dr. Pirngadi Medan Hospital, networking hospitals and private clinics throughout Medan from Januray 2013-March 2014. Population: Reproductive aged women complaining menstrual pain, abdominal located bulging, and/or infertility. Through consecutive sampling, patients suspected with endometriosis and meeting the inclusion criteria were taken as samples. The case group comprised of women diagnosed with endometriosis whereas the control group consisted of non endometriosis women.Methods: Visiting gynecology outpatient clinic patients were taken a complete history, and underwent physical/gynecological, sonographic examinations to determine an indication to perform a laparoscopy/laparotomy and, if present, a laparoscopy was scheduled to take place during the proliferation phase. Presence of endometriosis was assessed during the procedure, and further confirmed by histopathologically reviewing peritoneal specimens. Patients diagnosed with endometriosis were categorized into the case group, after which severity degrees were determined based on the Revised Classification of the American Sociey for Reproductive Medicine 1997. Non endometriosis patients were