Clinical observation on pretreatment of 98 patients with infertility combined with ovarian dysfunction

Objective:To observe the clinical curative effect of artificial cycle pretreatment before ovarian stimulation in the patients with infertility combined with ovarian dysfunction.Methods:Ninety-eight patients with infertility combined with ovarian dysfunction who were treated in the hospital from April 2009 to July 2010 were selected,then they were divided into unsuccessful in vitro fertilization(IVF) group(29 patients),premature ovarian failure(POF) group(20 patients),and ovarian dysfunction group(49 patients).From the view of life-network regulation,the patients in the three groups were treated with traditional Chinese medicine(the main therapy) plus appropriate estrogen and Tiaojingcuyun pills for three months,at the same time,all the patients received psychotherapy for more than half a year.The symptoms,ovulation rates,pregnancy rates,and the changes of serum sex hormones on the third day of menstrual cycle after treatment in the three groups were observed.Results:After treatment,the general symptoms of the patients in the three groups were improved significantly,there was no statistically significant difference in the serum estradiol level among the three groups(P0.05),the serum follicle stimulating hormone(FSH) levels decreased significantly(P0.05);after pretreatment,the pregnancy rate was 30.16%(30/98),the ovulation rate increased from 13.27%(13/98) before pretreatment to 51.02%(50/98)(P0.05).Conclusion:Pretreatment can relieve the clinical symptoms of patients with ovarian dysfunction,reduce serum FSH level,and improve clinical ovulation rate and pregnancy rate.