Comprehensive diagnostics of the eye-cornea structure based on the extended techniques of polarization-sensitive optical-coherence tomography

2025 · doi:10.22541/au.174075153.35120603/v1
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Abstract

We present a universal technique for non-invasive diagnostics of thin multilayer optically-transparent tissues, based on the polarization-sensitive optical-coherence tomography. To reach higher diagnostic accuracy, we revisit the model of the cornea structure, and re-consider physical features of the interaction of light with the tissue structural elements. In the scheme proposed, the probing beam is algorithmically adjustable such that the x -polarized radiation impinges each consecutive structural layer; the object beam is formed by the reflection and back-scattering. Its characteristics are found analytically and numerically within the framework of the polarized Monte-Carlo model and the Jones matrix formalism. A modified Mach-Zehnder interferometer with orthogonal polarization channels enables to eliminate the object-signal depolarization caused by stochastic scattering, and facilitates evaluation of the refractive indices and bi-refringence of the tissue elements. The technique permits longitudinal (in depth) and transverse scanning of the object, providing a complete 3D mapping of the cornea structure. Supplementary Material File (oct2025_jbp.docx) - Download - 19.05 MB Information & Authors Information Version history Copyright This work is licensed under a Non Exclusive No Reuse License. Collection

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Authors Metrics & Citations Metrics Article Usage 370views 187downloads Citations Download citation O.V. Angelsky, A.Y. Bekshaev, C.Yu. Zenkova, et al. Comprehensive diagnostics of the eye-cornea structure based on the extended techniques of polarization-sensitive optical-coherence tomography. Authorea. 28 February 2025. DOI: https://doi.org/10.22541/au.174075153.35120603/v1 DOI: https://doi.org/10.22541/au.174075153.35120603/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. For more information or tips please see 'Downloading to a citation manager' in the Help menu.

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last seen: 2026-05-20T01:45:00.602351+00:00