Aspiration and tetracycline sclerotherapy for management of simple ovarian cysts
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Ultrasound-guided aspiration and tetracycline sclerotherapy effectively treated simple ovarian cysts, with only one case requiring subsequent surgery and no reported recurrences.
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Abstract
OBJECTIVE: To evaluate the procedure of aspiration and tetracycline sclerotherapy in the management of simple ovarian cysts. METHODS: Twenty-five cases of simple ovarian cysts were subjected to cyst fluid aspiration and 5% tetracycline injection under ultrasound guidance. Cytological examination of the aspirated fluid was carried out in 24 cases and the patients were followed for 6-36 months. RESULTS: Cytology revealed a cellular sediment in 18 cases (simple cysts), follicular cells in four cases (follicular cysts), and blood and hemosiderin-laden macrophages in two cases (endometriosis); subsequent surgery was required in only one case (endometriosis). CONCLUSIONS: The procedure of aspiration and tetracycline sclerotherapy was easy, safe and acceptable, with no recurrences. It appears to be a valid alternative to cyst aspiration in the management of simple ovarian cysts.
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Cited by (7)
- Ethanol Sclerotherapy for Endometriomas in Infertile Women: A Narrative Review 2024
- Doxycycline reduces MMP-2 activity and inhibits invasion of 12Z epithelial endometriotic cells as well as MMP-2 and -9 activity in primary endometriotic stromal cells in vitro 2019
- Sclerotherapy with Ethanol: An Effective and Safe Alternative to Potentially Complex Surgical Treatment of Recurrent Ovarian Endometrioma 2015
- In situ methotrexate injection after transvaginal ultrasound-guided aspiration of ovarian endometriomas: A randomized controlled trial 2011
- Effectiveness of ultrasound-guided aspiration and sclerotherapy with 95% ethanol for treatment of recurrent ovarian endometriomas 2008
- Management of Ovarian Cysts with Aspiration and Methotrexate Injection 2005
- Sclerotherapy with 5% tetracycline is a simple alternative to potentially complex surgical treatment of ovarian endometriomas before in vitro fertilization 2004
Source provenance
- europepmc
- last seen: 2026-06-04T01:30:01.192114+00:00
- openalex
- last seen: 2026-06-04T00:00:01.174412+00:00
- pubmed
- last seen: 2026-05-13T22:11:13.665691+00:00
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