Aspiration and tetracycline sclerotherapy for management of simple ovarian cysts

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Ultrasound-guided aspiration and tetracycline sclerotherapy effectively treated simple ovarian cysts, with only one case requiring subsequent surgery and no reported recurrences.

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Abstract

OBJECTIVE: To evaluate the procedure of aspiration and tetracycline sclerotherapy in the management of simple ovarian cysts. METHODS: Twenty-five cases of simple ovarian cysts were subjected to cyst fluid aspiration and 5% tetracycline injection under ultrasound guidance. Cytological examination of the aspirated fluid was carried out in 24 cases and the patients were followed for 6-36 months. RESULTS: Cytology revealed a cellular sediment in 18 cases (simple cysts), follicular cells in four cases (follicular cysts), and blood and hemosiderin-laden macrophages in two cases (endometriosis); subsequent surgery was required in only one case (endometriosis). CONCLUSIONS: The procedure of aspiration and tetracycline sclerotherapy was easy, safe and acceptable, with no recurrences. It appears to be a valid alternative to cyst aspiration in the management of simple ovarian cysts.

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Condition tags

endometriosis

MeSH descriptors

Ovarian Cysts Sclerosing Solutions Sclerotherapy Suction Tetracyclines Adult Female Humans Middle Aged Ovarian Cysts Sclerosing Solutions Tetracyclines Treatment Outcome

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europepmc
last seen: 2026-06-04T01:30:01.192114+00:00
openalex
last seen: 2026-06-04T00:00:01.174412+00:00
pubmed
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