The Neuroanatomy of Female Pelvic Pain

In: Pain in Women · 2012 · pp. 17–58 · doi:10.1007/978-1-4419-7113-5_2 · W1440319277
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Female pelvic pain arises from complex interactions between somatic and visceral innervations converging on spinal cord circuitry, modulated by descending signals influenced by hormonal and psychological states.

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This chapter examines neuroanatomical pathways underlying female pelvic pain by describing how somatic and visceral afferent fibers travel via somatic and autonomic-related nerves to converge on shared spinal cord circuitry in the sacral and thoracolumbar regions. It highlights that pain patterning is complicated by convergent somatovisceral processing and further modulated by strong descending influences from the cerebrum and brainstem, whose effects are shaped by physiological states (including hormonal factors) and psychological states. A major caveat is that uncovering the precise origins of blended somatovisceral pain patterns in individuals is described as inherently difficult. This paper is centrally about endometriosis—though it is not specifically focused on endometriosis, it provides a somatovisceral neuroanatomical framework relevant to the pelvic pain mechanisms that endometriosis can produce.

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Abstract

The female pelvis is innervated through primary afferent fibers that course in nerves related to both the somatic and autonomic nervous systems. The somatic pelvis includes the bony pelvis, its ligaments, and its surrounding skeletal muscle of the urogenital and anal triangles, whereas the visceral pelvis includes the endopelvic fascial lining of the levator ani and the organ systems that it surrounds such as the rectum, reproductive organs, and urinary bladder. Uncovering the origin of pelvic pain patterns created by the convergence of these two separate primary afferent fiber systems – somatic and visceral – on common neuronal circuitry in the sacral and thoracolumbar spinal cord can be a very difficult process. Diagnosing these blended somatovisceral pelvic pain patterns in the female is further complicated by the strong descending signals from the cerebrum and brainstem to the dorsal horn neurons that can significantly modulate the perception of pain. These descending systems are themselves significantly influenced by both the physiological (such as hormonal) and psychological (such as emotional) states of the individual further distorting the intensity, quality, and localization of pain from the pelvis. Access this chapter Tax calculation will be finalised at checkout Purchases are for personal use only Similar content being viewed by others

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(eds) Pain in Women. Springer, New York, NY. https://doi.org/10.1007/978-1-4419-7113-5_2 Download citation DOI: https://doi.org/10.1007/978-1-4419-7113-5_2 Published: Publisher Name: Springer, New York, NY Print ISBN: 978-1-4419-7112-8 Online ISBN: 978-1-4419-7113-5 eBook Packages: MedicineMedicine (R0)

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