Herlyn-Werner-Wunderlich Syndrome: A Very Rare Urogenital Anomaly in a Teenage Girl

In: The Journal of Emergency Medicine · 2014 · vol. 48(3) , pp. e73–e75 · doi:10.1016/j.jemermed.2014.09.064 · PMID:25499400 · W1975085906
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AI-generated summary by claude@2026-06, 2026-06-10

This case report describes the presentation and management of a teenage girl diagnosed with Herlyn-Werner-Wunderlich syndrome, a rare urogenital anomaly characterized by didelphys uterus, obstructed hemivagina, and ipsilateral renal agenesis.

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Abstract

BackgroundHerlyn-Werner-Wunderlich (HWW) syndrome is an uncommon variant of Müllerian duct anomalies, consisting of uterine didelphys, obstructed hemivagina, and ipsilateral renal agenesis. It usually presents in a post-pubertal adolescent or adult woman in whom hematometrocolpos produces a pronounced mass effect and pain on the side of the obstructed hemivagina.Case reportWe report the case of a 13-year-old girl who presented to the emergency radiology department with sudden onset of severe pain at the right lower quadrant of the abdomen; imaging confirmed the diagnosis of HWW syndrome. WHY SHOULD AN EMERGENCY PHYSICIAN BE AWARE OF THIS?: When unilateral renal agenesis and uterus didelphys coexist, the first thing that the physician should remember is to confirm or refute the presence of a blind vagina for diagnosis of HWW syndrome.

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