WITHDRAWN: Interaction Between Neuroimmune Activation Mechanisms in Epilepsy: The S100b Signalling Network and Brain-gut-bio-axis | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Systematic Review WITHDRAWN: Interaction Between Neuroimmune Activation Mechanisms in Epilepsy: The S100b Signalling Network and Brain-gut-bio-axis Jianxun He, Yan Bo, Beilei Li, Jing Hao, Chuhan Miao, Ren Sha, and 1 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-3712801/v2 This work is licensed under a CC BY 4.0 License Status: Posted Version 2 posted You are reading this latest preprint version Show more versions Editorial Note 14 March, 2025. The full text of this preprint has been withdrawn by the authors since they no longer stand by the findings/conclusions of this work. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author. 18 February, 2026. Research Square has updated the withdrawal statement to reflect that this preprint was withdrawn due to an unresolved authorship dispute. In addition, readers are advised that the published version of this work is currently subject to an Expression of Concern regarding potential overlapping text with a previously published article that was not appropriately attributed. These concerns are currently under review by the journal. Editorial notes are used to provide important context regarding the topic of a preprint or to alert readers to potential issues concerning that preprint or a downstream publication associated with it. For more information on editorial notes, see our Editorial Policies . Abstract 14 March, 2025. The full text of this preprint has been withdrawn by the authors since they no longer stand by the findings/conclusions of this work. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author. 18 February, 2026. Research Square has updated the withdrawal statement to reflect that this preprint was withdrawn due to an unresolved authorship dispute. In addition, readers are advised that the published version of this work is currently subject to an Expression of Concern regarding potential overlapping text with a previously published article that was not appropriately attributed. These concerns are currently under review by the journal. Neurology Full Text 14 March, 2025. The full text of this preprint has been withdrawn by the authors since they no longer stand by the findings/conclusions of this work. Therefore, the authors do not wish this work to be cited as a reference. Questions should be directed to the corresponding author. 18 February, 2026. Research Square has updated the withdrawal statement to reflect that this preprint was withdrawn due to an unresolved authorship dispute. In addition, readers are advised that the published version of this work is currently subject to an Expression of Concern regarding potential overlapping text with a previously published article that was not appropriately attributed. These concerns are currently under review by the journal. Cite Share Download PDF Status: Posted Version 2 posted You are reading this latest preprint version Show more versions Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. 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Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-3712801","acceptedTermsAndConditions":true,"allowDirectSubmit":true,"archivedVersions":[],"articleType":"Systematic Review","associatedPublications":[],"authors":[{"id":428997028,"identity":"a3752d09-7cf6-4565-a493-39e094c678fa","order_by":0,"name":"Jianxun He","email":"","orcid":"","institution":"Gansu Provincial Maternity and Child Care Hospital","correspondingAuthor":false,"prefix":"","firstName":"Jianxun","middleName":"","lastName":"He","suffix":""},{"id":428997029,"identity":"b44bb056-046c-418e-b398-05ddb55ea79c","order_by":1,"name":"Yan Bo","email":"","orcid":"","institution":"Northwest Minzu University","correspondingAuthor":false,"prefix":"","firstName":"Yan","middleName":"","lastName":"Bo","suffix":""},{"id":428997030,"identity":"b636c192-b063-4912-9c40-1476eb396355","order_by":2,"name":"Beilei Li","email":"","orcid":"","institution":"Shanghai Xuhui Central Hospital","correspondingAuthor":false,"prefix":"","firstName":"Beilei","middleName":"","lastName":"Li","suffix":""},{"id":428997031,"identity":"0d332882-925b-4b2b-bb42-6f28117ad952","order_by":3,"name":"Jing Hao","email":"","orcid":"","institution":"University of Leeds","correspondingAuthor":false,"prefix":"","firstName":"Jing","middleName":"","lastName":"Hao","suffix":""},{"id":428997032,"identity":"74999287-3ca9-4013-b260-43eff530302e","order_by":4,"name":"Chuhan Miao","email":"data:image/png;base64,iVBORw0KGgoAAAANSUhEUgAAAZAAAAAyAQMAAABI0h/eAAAABlBMVEX///8AAABVwtN+AAAACXBIWXMAAA7EAAAOxAGVKw4bAAAA+UlEQVRIiWNgGAWjYDAC/v6HDxIqJOT44SISbAwMjA0JuLVInGE2+HDGxliyAconrIUhh01yZkta4oYDxGoxOHD2mDRvw2Fj4+OHjz0uqLCrY5BuS5Ng3JGGW8vhvmRr3h2H5czOpKUbzziTLMEgc+yYBOOZHDy2HDC8zXvmsLHZDR4zad62A0CHpbdJMLZV4NGSYABUeThx8wyQln9EackxkpzZBvS+BEhLA0hLGtBhbbgdJnnjWDI4kCXOpKVJ8xxLlmyTSEu2SGzD7X2+880HIVHZfviYNE+NHT+/RJrhjY9tyTi1YAI2EJFAgoZRMApGwSgYBZgAAJMLVLaq2IYJAAAAAElFTkSuQmCC","orcid":"","institution":"The Chinese University of Hong Kong","correspondingAuthor":true,"prefix":"","firstName":"Chuhan","middleName":"","lastName":"Miao","suffix":""},{"id":428997033,"identity":"ac8a5fd8-280d-49a3-9c11-e5e430971962","order_by":5,"name":"Ren Sha","email":"","orcid":"","institution":"Henan Polytechnic University","correspondingAuthor":false,"prefix":"","firstName":"Ren","middleName":"","lastName":"Sha","suffix":""},{"id":428997034,"identity":"65d3fb9e-1cff-4fbd-b0e4-bb2964553ec6","order_by":6,"name":"Haodong Yu","email":"","orcid":"","institution":"Jiangxi Police Academy","correspondingAuthor":false,"prefix":"","firstName":"Haodong","middleName":"","lastName":"Yu","suffix":""}],"badges":[],"createdAt":"2023-12-06 03:32:08","currentVersionCode":2,"declarations":{"humanSubjects":false,"vertebrateSubjects":false,"conflictsOfInterestStatement":true,"humanSubjectEthicalGuidelines":false,"humanSubjectConsent":false,"humanSubjectClinicalTrial":false,"humanSubjectCaseReport":false,"vertebrateSubjectEthicalGuidelines":false},"doi":"10.21203/rs.3.rs-3712801/v2","doiUrl":"https://doi.org/10.21203/rs.3.rs-3712801/v2","draftVersion":[],"editorialEvents":[],"editorialNote":"\u003cp\u003e14 March, 2025. 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