Ovarian Endometrioid Adenocarcinoma Coexistent with Benign and Borderline Endometrioid Adenofibroma: A Case Report

Kimio Ushijima, Takashi Nishida, Yasunori Muraoka, T Sugiyama, Naofumi Okura, Atsuhiko Shinagawa, Kiyohisa Imaishi, M Yakushiji
In: Journal of Obstetrics and Gynaecology Research · 1998 · vol. 24(2) , pp. 161–166 · doi:10.1111/j.1447-0756.1998.tb00069.x · PMID:9631607 · W2012530442
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This case report describes a rare ovarian tumor in a 64-year-old woman comprising endometrioid adenocarcinoma coexistent with benign and borderline endometrioid adenofibroma.

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Abstract

A well-differentiated endometrioid adenocarcinoma coexistent with benign and borderline-malignant endometrioid adenofibroma was found in the ovary of a 64-year-old woman. She had vaginal bleeding caused by simple hyperplasia of the endometrium due to high levels of sex steroid hormones. A FIGO stage Ia solid ovarian tumor was identified. It was composed of irregularly shaped endometriotic glands with benign and borderline malignant cytologic features embedded in abundant fibromatous stroma. Well-differentiated malignant epithelium was adjacent to these areas, but fibromatous stroma was not predominant. She was treated by surgery and three cycles of chemotherapy. This paper describes this unusual tumor and reviews the literature.

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