SUBSTITUTED 16,17-ANNELLATED STERIOD COMPOUNDS FOR USE IN WOMENS HEALTHCARE

DIJCKS FREDERICUS ANTONIUS, LOOZEN HUBERT JAN JOZEF, ADDO SAMIRA, EDERVEEN ANTONIUS GERARDUS HENDRIKUS
2010
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Abstract

The present invention relates to substituted steroid compounds having the formula Wherein R1 is H or halogen R2 is H, (1C-4C)alkyl, (1C-4C)acyl, glucuronyl or sulfamoyl R3 is H or halogen R4 is H, (1C-4C)alkyl, (2C-4C)alkenyl or (2C-4C)alkynyl R5 is methyl or ethyl R6 is H or methyl R7 is H or methyl R8 is H or acyl for use in the treatment and prevention of endometriosis, for contraception, for hormonal therapy in perimenopausal and post-menopausal women, for the treatment of osteoporosis and for the treatment uterine fibroids and other menstrual-related disorders, such as dysfunctional uterine bleeding.

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europepmc
last seen: 2026-07-06T06:10:23.601157+00:00