Twenty-One Day Administration of Dienogest Reversibly Suppresses Gonadotropins and Testosterone in Normal Men
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This study investigated the effects of 21-day dienogest administration on reproductive hormones and metabolic parameters in normal men, finding reversible suppression of gonadotropins and testosterone.
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Abstract
Androgen-progestin combinations are promising male contraceptive regimens. Optimization of these regimens includes the development of new progestins with more favorable biological properties. In this context we tested the effects of the progestin dienogest (DNG) on reproductive hormones and metabolic parameters in men.
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