Impact of cellulose supramolecular structure on its carboxymethylation reaction activity

Impact of cellulose supramolecular structure on its carboxymethylation reaction activity | Research Square window.SnipcartSettings = { analytics: { enabled: false } }; (function() { var accessVector = localStorage.getItem('access_vector') || ''; window.dataLayer = window.dataLayer || []; if (accessVector) { window.dataLayer.push({ user: { profile: { profileInfo: { snid: accessVector } } } }); } })(); (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0],j=d.createElement(s),dl=l!='dataLayer'?'&l='+l:'';j.async=true;j.src='https://www.googletagmanager.com/gtm.js?id='+i+dl;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-K279D39R'); Browse Preprints In Review Journals COVID-19 Preprints AJE Video Bytes Research Tools Research Promotion AJE Professional Editing AJE Rubriq About Preprint Platform In Review Editorial Policies Our Team Advisory Board Help Center Sign In Submit a Preprint Cite Share Download PDF Research Article Impact of cellulose supramolecular structure on its carboxymethylation reaction activity Sherzod Yuldoshov, Khaydar Yunusov, Ilkhom Goyipnazarov, Abdushkur Sarymsakov, and 2 more This is a preprint; it has not been peer reviewed by a journal. https://doi.org/ 10.21203/rs.3.rs-3744129/v1 This work is licensed under a CC BY 4.0 License Status: Under Review Version 1 posted 5 You are reading this latest preprint version Abstract The reaction activity of cellulose samples is determined according to their supramolecular structure, especially the degree of crystallinity. The carboxymethylation reaction kinetics of cotton cellulose (CC), powder cellulose (PC) and microcrystalline cellulose (MCC), with different degrees of crystallinity, were studied by the solid-phase method and in an ethanol-water solution medium. In the row of CC, MCC, and PC with different supramolecular structures, it was found that with decreasing crystallinity degree of the raw materials, during carboxymethylation by the solid-phase method and in an ethanol-water solution medium, the degree of substitution (DS) of sodium carboxymethylcellulose (Na-CMC) increased. In this row the activation energy values of the carboxymethylation reaction of CC, MCC, and PC were 31.12, 19.75, and 15.72 kJ/mol, respectively, by the solid-phase method. Furthermore, the activation energies of the carboxymethylation reaction of CC, MCC, and PC were 59.95, 26.15, and 23.68 kJ/mol, respectively, in an ethanol-water solution medium. Decreasing activation energies led to an increase in the reaction activity, which, after CC, MCC, and PC carboxymethylation, the DS of Na-CMC reached 0.61, 0.80, and 0.87, respectively, using the solid-phase method. In an ethanol solution medium, the DS values of Na-CMC reached 0.86, 1.04, and 1.24 after carboxymethylation of the CC, MCC, and PC, respectively. sodium carboxymethylcellulose supramolecular structure cellulose reaction rate activation energy Full Text Additional Declarations No competing interests reported. Supplementary Files GraphicalAbstractText.docx Cite Share Download PDF Status: Under Review Version 1 posted Reviewers agreed at journal 24 Dec, 2023 Reviewers invited by journal 24 Dec, 2023 Editor assigned by journal 18 Dec, 2023 Submission checks completed at journal 18 Dec, 2023 First submitted to journal 12 Dec, 2023 You are reading this latest preprint version Research Square lets you share your work early, gain feedback from the community, and start making changes to your manuscript prior to peer review in a journal. As a division of Research Square Company, we’re committed to making research communication faster, fairer, and more useful. We do this by developing innovative software and high quality services for the global research community. Our growing team is made up of researchers and industry professionals working together to solve the most critical problems facing scientific publishing. Also discoverable on Platform About Our Team In Review Editorial Policies Advisory Board Help Center Resources Author Services Accessibility API Access RSS feed Manage Cookie Preferences © Research Square 2026 | ISSN 2693-5015 (online) Privacy Policy Terms of Service Do Not Sell My Personal Information {"props":{"pageProps":{"initialData":{"identity":"rs-3744129","acceptedTermsAndConditions":true,"allowDirectSubmit":false,"archivedVersions":[],"articleType":"Research Article","associatedPublications":[],"authors":[{"id":264260858,"identity":"3fee7ccb-1fcb-41d2-98c5-26c59e95c5a7","order_by":0,"name":"Sherzod Yuldoshov","email":"","orcid":"","institution":"Institute of Polymer Chemistry and Physics of the Academy of Sciences of the Republic of Uzbekistan","correspondingAuthor":false,"prefix":"","firstName":"Sherzod","middleName":"","lastName":"Yuldoshov","suffix":""},{"id":264260859,"identity":"65a44081-9683-4225-a011-89acf52b1cbc","order_by":1,"name":"Khaydar 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activity","fulltext":[],"fulltextSource":"","fullText":"","funders":[],"hasAdminPriorityOnWorkflow":false,"hasManuscriptDocX":false,"hasOptedInToPreprint":true,"hasPassedJournalQc":"","hasAnyPriority":false,"hideJournal":false,"highlight":"","institution":"","isAcceptedByJournal":false,"isAuthorSuppliedPdf":true,"isDeskRejected":"","isHiddenFromSearch":false,"isInQc":false,"isInWorkflow":false,"isPdf":true,"isPdfUpToDate":true,"isWithdrawnOrRetracted":false,"journal":{"display":true,"email":"[email protected]","identity":"cellulose","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"cels","sideBox":"Learn more about [Cellulose](https://www.springer.com/journal/10570)","snPcode":"10570","submissionUrl":"https://submission.nature.com/new-submission/10570/3","title":"Cellulose","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"em","reportingPortfolio":"Springer Hybrid","inReviewEnabled":true,"inReviewRevisionsEnabled":false},"keywords":"sodium carboxymethylcellulose, supramolecular structure, cellulose, reaction rate, activation energy","lastPublishedDoi":"10.21203/rs.3.rs-3744129/v1","lastPublishedDoiUrl":"https://doi.org/10.21203/rs.3.rs-3744129/v1","license":{"name":"CC BY 4.0","url":"https://creativecommons.org/licenses/by/4.0/"},"manuscriptAbstract":"\u003cp\u003eThe reaction activity of cellulose samples is determined according to their supramolecular structure, especially the degree of crystallinity. The carboxymethylation reaction kinetics of cotton cellulose (CC), powder cellulose (PC) and microcrystalline cellulose (MCC), with different degrees of crystallinity, were studied by the solid-phase method and in an ethanol-water solution medium. In the row of CC, MCC, and PC with different supramolecular structures, it was found that with decreasing crystallinity degree of the raw materials, during carboxymethylation by the solid-phase method and in an ethanol-water solution medium, the degree of substitution (DS) of sodium carboxymethylcellulose (Na-CMC) increased. In this row the activation energy values of the carboxymethylation reaction of CC, MCC, and PC were 31.12, 19.75, and 15.72 kJ/mol, respectively, by the solid-phase method. Furthermore, the activation energies of the carboxymethylation reaction of CC, MCC, and PC were 59.95, 26.15, and 23.68 kJ/mol, respectively, in an ethanol-water solution medium. Decreasing activation energies led to an increase in the reaction activity, which, after CC, MCC, and PC carboxymethylation, the DS of Na-CMC reached 0.61, 0.80, and 0.87, respectively, using the solid-phase method. In an ethanol solution medium, the DS values of Na-CMC reached 0.86, 1.04, and 1.24 after carboxymethylation of the CC, MCC, and PC, respectively.\u003c/p\u003e","manuscriptTitle":"Impact of cellulose supramolecular structure on its carboxymethylation reaction activity","msid":"","msnumber":"","nonDraftVersions":[{"code":1,"date":"2024-01-04 08:11:43","doi":"10.21203/rs.3.rs-3744129/v1","editorialEvents":[{"type":"communityComments","content":0},{"type":"reviewerAgreed","content":"666586ed-03bc-442c-ad47-1cc2f371f66b","date":"2023-12-24T07:37:07+00:00","index":"hide","fulltext":""},{"type":"reviewersInvited","content":"","date":"2023-12-24T07:25:50+00:00","index":"","fulltext":""},{"type":"editorAssigned","content":"","date":"2023-12-18T10:32:04+00:00","index":"","fulltext":""},{"type":"checksComplete","content":"","date":"2023-12-18T10:32:03+00:00","index":"","fulltext":""},{"type":"submitted","content":"Cellulose","date":"2023-12-12T13:39:20+00:00","index":"","fulltext":""}],"status":"published","journal":{"display":true,"email":"[email protected]","identity":"cellulose","isNatureJournal":false,"hasQc":true,"allowDirectSubmit":false,"externalIdentity":"cels","sideBox":"Learn more about [Cellulose](https://www.springer.com/journal/10570)","snPcode":"10570","submissionUrl":"https://submission.nature.com/new-submission/10570/3","title":"Cellulose","twitterHandle":"","acdcEnabled":true,"dfaEnabled":true,"editorialSystem":"em","reportingPortfolio":"Springer Hybrid","inReviewEnabled":true,"inReviewRevisionsEnabled":false}}],"origin":"","ownerIdentity":"f10a0ba4-6eb4-48dc-8859-68f4326fbd96","owner":[],"postedDate":"January 4th, 2024","published":true,"recentEditorialEvents":[],"rejectedJournal":[],"revision":"","amendment":"","status":"under-review","subjectAreas":[],"tags":[],"updatedAt":"2024-01-04T08:11:44+00:00","versionOfRecord":[],"versionCreatedAt":"2024-01-04 08:11:43","video":"","vorDoi":"","vorDoiUrl":"","workflowStages":[]},"version":"v1","identity":"rs-3744129","journalConfig":"researchsquare"},"__N_SSP":true},"page":"/article/[identity]/[[...version]]","query":{"redirect":"/article/rs-3744129","identity":"rs-3744129","version":["v1"]},"buildId":"qtupq5eGEP_6zYnWcrvyt","isFallback":false,"isExperimentalCompile":false,"dynamicIds":[84888],"gssp":true,"scriptLoader":[]}