Hyperamylasemia associated with endometrioid carcinoma of the ovary: case report and immunohistochemical study

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This report details a case of hyperamylasemia in ovarian endometrioid carcinoma, with amylase levels normalizing post-surgery and tumor cells showing intracytoplasmic amylase.

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Abstract

Hyperamylasemia was noted in a patient with a stage I well-differentiated endometrioid adenocarcinoma of the ovary. Serum levels of amylase decreased rapidly after removal of the ovarian tumor. Immunohistochemical study revealed intracytoplasmic localization of amylase in many tumor cells. Although it was strongly suspected that the tumor cells had produced amylase in the present patient, further studies are required to be sure that amylase can be considered an important tumor marker for the endometrioid type of ovarian tumors.

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Condition tags

endometriosis

MeSH descriptors

Adenocarcinoma Amylases Endometriosis Ovarian Neoplasms Adenocarcinoma Adenocarcinoma Adenocarcinoma Adenocarcinoma Amylases Amylases Amylases Amylases Endometriosis Endometriosis Endometriosis Endometriosis Female Humans Middle Aged Ovarian Neoplasms

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Source provenance

europepmc
last seen: 2026-08-12T06:07:16.479679+00:00
pubmed
last seen: 2026-05-13T22:09:35.489789+00:00
unpaywall
last seen: 2026-05-14T19:30:52.867331+00:00
License: public-domain-us · commercial use OK · attribution required
Courtesy of the U.S. National Library of Medicine