Using a learning health system to integrate Peer Support in Early Intervention Services for psychosis in Quebec: Protocol for a Participatory, Mixed-Methods Study (the PAIRPEP project)

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Introduction: Since 2019, a rapid learning health system for Quebec’s Early Intervention Services for psychosis named SARPEP (Système Apprenant Rapide pour les programmes de Premiers Épisodes Psychotiques) operates to bridge the evidence-practice gap across the province. Despite strong stakeholder support and government recommendations, peer support services remained poorly available. To address this gap, since 2023, the PAIRPEP project was co-developed to support and evaluate the implementation of peer support and family peer support. This paper describes the co-designed study protocol, embedded within this learning health system. Methods: : This participatory, mixed-methods study aims to examine the PAIRPEP intervention implementation longitudinally over 3 years across 12 Early Intervention Services and its impact on multiple stakeholders. Informed by the Medical Research Council framework for complex interventions, the project includes a co-designed (with multiple stakeholders) multimodal capacity-building program with specific components developed to overcome barriers to peer support and family peer support integration. Quantitative questionnaires are collected every four months from clinicians and continuously from youth and families (questionnaires, satisfaction surveys) using the learning health system electronic platform. Focus groups are conducted annually over three years with eight stakeholder groups. The analysis integrates findings using thematic synthesis and joint displays to assess convergence and divergence across methods and perspectives. Results: and conclusion: This protocol paper outlines the study’s co-design, procedures, and anticipated contributions. Embedding large-scale innovative intervention implementation (such as peer support) within an RLHS can foster real-time feedback, iterative refinement, and inform clinical practice and policies.
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Using a learning health system to integrate Peer Support in Early Intervention Services for psychosis in Quebec: Protocol for a Participatory, Mixed-Methods Study (the PAIRPEP project) | Authorea try { document.documentElement.classList.add('js'); } catch (e) { } var _gaq = _gaq || []; _gaq.push(['_setAccount', 'G-8VDV14Y67G']); _gaq.push(['_trackPageview']); (function() { var ga = document.createElement('script'); ga.type = 'text/javascript'; ga.async = true; ga.src = ('https:' == document.location.protocol ? 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Data may be preliminary. 16 May 2025 V1 Latest version Share on Using a learning health system to integrate Peer Support in Early Intervention Services for psychosis in Quebec: Protocol for a Participatory, Mixed-Methods Study (the PAIRPEP project) Authors : Beatrice Todescoᵃ , Srividya Iyer 0000-0001-5367-9086 , Manuela Ferrari , Marc-André Roy 0000-0002-0123-6651 , Marie-Helene Morin , Julie Marguerite Deschênesᵃ , Gabriel Julienᵃ , Annie Bosséᵃ , Mary Anne Levasseur , and Amal Abdel-Baki [email protected] Authors Info & Affiliations https://doi.org/10.22541/au.174738435.53307949/v1 Published Early Intervention in Psychiatry Version of record Peer review timeline 288 views 111 downloads Contents Abstract Supplementary Material Information & Authors Metrics & Citations View Options References Figures Tables Media Share Abstract Introduction: Since 2019, a rapid learning health system for Quebec’s Early Intervention Services for psychosis named SARPEP (Système Apprenant Rapide pour les programmes de Premiers Épisodes Psychotiques) operates to bridge the evidence-practice gap across the province. Despite strong stakeholder support and government recommendations, peer support services remained poorly available. To address this gap, since 2023, the PAIRPEP project was co-developed to support and evaluate the implementation of peer support and family peer support. This paper describes the co-designed study protocol, embedded within this learning health system. Methods: This participatory, mixed-methods study aims to examine the PAIRPEP intervention implementation longitudinally over 3 years across 12 Early Intervention Services and its impact on multiple stakeholders. Informed by the Medical Research Council framework for complex interventions, the project includes a co-designed (with multiple stakeholders) multimodal capacity-building program with specific components developed to overcome barriers to peer support and family peer support integration. Quantitative questionnaires are collected every four months from clinicians and continuously from youth and families (questionnaires, satisfaction surveys) using the learning health system electronic platform. Focus groups are conducted annually over three years with eight stakeholder groups. The analysis integrates findings using thematic synthesis and joint displays to assess convergence and divergence across methods and perspectives. Results and conclusion: This protocol paper outlines the study’s co-design, procedures, and anticipated contributions. Embedding large-scale innovative intervention implementation (such as peer support) within an RLHS can foster real-time feedback, iterative refinement, and inform clinical practice and policies. Supplementary Material File (fig.1 co-development and implementation phases of the pairpep intervention.pptx) Download 49.45 KB File (fig.2 pairpep data collection, analysis and sharing timeline.pptx) Download 60.06 KB File (manuscript - using a learning health system to integrate peer support in eis - early intervention in psychiatry.docx) Download 61.07 KB File (table 1. core elements of mrc framework applied to the pairpep initiative.docx) Download 19.12 KB File (table 2 inclusion and exclusion criteria.docx) Download 16.48 KB File (table 3. mixed-method matrix.docx) Download 32.30 KB Information & Authors Information Version history V1 Version 1 16 May 2025 Peer review timeline Published Early Intervention in Psychiatry Version of Record 14 Oct 2025 Published Copyright This work is licensed under a Non Exclusive No Reuse License. Collection Early Intervention in Psychiatry Keywords early intervention services for psychosis implementation learning health system mixed methods peer support Authors Affiliations Beatrice Todescoᵃ Centre de Recherche du Centre Hospitalier de l'Universite de Montreal View all articles by this author Srividya Iyer 0000-0001-5367-9086 McGill University Department of Psychiatry View all articles by this author Manuela Ferrari McGill University Department of Psychiatry View all articles by this author Marc-André Roy 0000-0002-0123-6651 Universite Laval Departement de Psychiatrie et Neurosciences View all articles by this author Marie-Helene Morin Universite du Quebec a Rimouski View all articles by this author Julie Marguerite Deschênesᵃ Centre de Recherche du Centre Hospitalier de l'Universite de Montreal View all articles by this author Gabriel Julienᵃ Centre de Recherche du Centre Hospitalier de l'Universite de Montreal View all articles by this author Annie Bosséᵃ Centre de Recherche du Centre Hospitalier de l'Universite de Montreal View all articles by this author Mary Anne Levasseur Centre de Recherche du Centre Hospitalier de l'Universite de Montreal View all articles by this author Amal Abdel-Baki [email protected] Centre de Recherche du Centre Hospitalier de l'Universite de Montreal View all articles by this author Metrics & Citations Metrics Article Usage 288 views 111 downloads .FvxKWukQNSOunydq8rnd { width: 100px; } Citations Download citation Beatrice Todescoᵃ, Srividya Iyer, Manuela Ferrari, et al. Using a learning health system to integrate Peer Support in Early Intervention Services for psychosis in Quebec: Protocol for a Participatory, Mixed-Methods Study (the PAIRPEP project). Authorea . 16 May 2025. DOI: https://doi.org/10.22541/au.174738435.53307949/v1 If you have the appropriate software installed, you can download article citation data to the citation manager of your choice. Simply select your manager software from the list below and click Download. For more information or tips please see 'Downloading to a citation manager' in the Help menu . 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