Assessment of WBCT Use in Trauma Patients: A National audit for Radiology Resource Management and Limiting Radiation Exposure

preprint OA: closed
📄 Open PDF Full text JSON View at publisher
AI-generated deep summary by claude@2026-07, 2026-07-04 · read from full text

This multicenter retrospective national audit assessed the “effective use” of whole-body CT (WBCT) in 1,367 trauma patients who underwent WBCT in seven radiology departments across Kuwait in 2022–2023, using American College of Radiology major blunt trauma guidelines. The authors collected demographics, injury mechanism, clinical indications, dose-length product and effective dose, and categorized WBCT results as negative versus positive (major versus minor injuries). They found 42.3% of scans had no significant findings, while 57.7% showed positive trauma-related results, with major injuries present in 38.8% of the positive cases; negative scans had a mean effective dose of 19.98 ± 10.26 mSv. A key limitation is that the study focuses on patients who already met inclusion criteria for WBCT per guidelines, without demonstrating prospective impact of any optimization strategy. The paper does not explicitly discuss endometriosis or adenomyosis; it was included in the corpus via a keyword match in the upstream search index.

Read from the paper's body, not the abstract. Not a substitute for reading the paper. No clinical advice. How this works

Abstract

ABSTRACT Introduction Whole-body computed tomography (WBCT) is often indiscriminately used in trauma cases. This study aimed to assess the effective use of WBCT in trauma patients across emergency departments in State of Kuwait, evaluate the true incidence of critical injuries, and minimize unnecessary radiation exposure. Methods This multicenter, retrospective study across seven radiology departments included 1,367 trauma patients who underwent WBCT between 2022 and 2023, according to the American College of Radiology guidelines. Data on age, sex, injury mechanism, clinical indications, dose-length product, and WBCT findings were collected and analyzed using IBM SPSS version 25. Results Of 1,367 referrals, 578 (42.3%) had no significant findings, while 789 (57.7%) showed positive trauma-related results. Among the positive findings, 530 patients (38.8%) had major injuries, including solid organ and vertebral column injuries. The most common causes of WBCT referrals were road traffic accidents (RTAs) (911 patients, 66.6%), falls from height (FFH) (182 patients, 13%), falls of heavy objects (112 patients, 8%), head trauma (82 patients, 6%), buggy accidents (28 patients, 2%) and others. Negative WBCT findings had a mean effective dose (ED) of 19.98 ± 10.26 mSv. Conclusions Positive WBCT findings were seen in 57.7% of cases, but the 42.3% negative findings rate, was significantly higher than the 20.4% average reported in similar centers in Europe such as UK and Germany, which highlights the need to optimize WBCT usage in emergency department to reduce unnecessary scans and minimize radiation exposure.
Full text 44,913 characters · extracted from preprint-html · click to expand
Assessment of WBCT Use in Trauma Patients: A National audit for Radiology Resource Management and Limiting Radiation Exposure | medRxiv /* */ /* */ <!-- <!-- /*! * yepnope1.5.4 * (c) WTFPL, GPLv2 */ (function(a,b,c){function d(a){return"[object Function]"==o.call(a)}function e(a){return"string"==typeof a}function f(){}function g(a){return!a||"loaded"==a||"complete"==a||"uninitialized"==a}function h(){var a=p.shift();q=1,a?a.t?m(function(){("c"==a.t?B.injectCss:B.injectJs)(a.s,0,a.a,a.x,a.e,1)},0):(a(),h()):q=0}function i(a,c,d,e,f,i,j){function k(b){if(!o&&g(l.readyState)&&(u.r=o=1,!q&&h(),l.onload=l.onreadystatechange=null,b)){"img"!=a&&m(function(){t.removeChild(l)},50);for(var d in y[c])y[c].hasOwnProperty(d)&&y[c][d].onload()}}var j=j||B.errorTimeout,l=b.createElement(a),o=0,r=0,u={t:d,s:c,e:f,a:i,x:j};1===y[c]&&(r=1,y[c]=[]),"object"==a?l.data=c:(l.src=c,l.type=a),l.width=l.height="0",l.onerror=l.onload=l.onreadystatechange=function(){k.call(this,r)},p.splice(e,0,u),"img"!=a&&(r||2===y[c]?(t.insertBefore(l,s?null:n),m(k,j)):y[c].push(l))}function j(a,b,c,d,f){return q=0,b=b||"j",e(a)?i("c"==b?v:u,a,b,this.i++,c,d,f):(p.splice(this.i++,0,a),1==p.length&&h()),this}function k(){var a=B;return a.loader={load:j,i:0},a}var l=b.documentElement,m=a.setTimeout,n=b.getElementsByTagName("script")[0],o={}.toString,p=[],q=0,r="MozAppearance"in l.style,s=r&&!!b.createRange().compareNode,t=s?l:n.parentNode,l=a.opera&&"[object Opera]"==o.call(a.opera),l=!!b.attachEvent&&!l,u=r?"object":l?"script":"img",v=l?"script":u,w=Array.isArray||function(a){return"[object Array]"==o.call(a)},x=[],y={},z={timeout:function(a,b){return b.length&&(a.timeout=b[0]),a}},A,B;B=function(a){function b(a){var a=a.split("!"),b=x.length,c=a.pop(),d=a.length,c={url:c,origUrl:c,prefixes:a},e,f,g;for(f=0;f<d;f++)g=a[f].split("="),(e=z[g.shift()])&&(c=e(c,g));for(f=0;f<b;f++)c=x[f](c);return c}function g(a,e,f,g,h){var i=b(a),j=i.autoCallback;i.url.split(".").pop().split("?").shift(),i.bypass||(e&&(e=d(e)?e:e[a]||e[g]||e[a.split("/").pop().split("?")[0]]),i.instead?i.instead(a,e,f,g,h):(y[i.url]?i.noexec=!0:y[i.url]=1,f.load(i.url,i.forceCSS||!i.forceJS&&"css"==i.url.split(".").pop().split("?").shift()?"c":c,i.noexec,i.attrs,i.timeout),(d(e)||d(j))&&f.load(function(){k(),e&&e(i.origUrl,h,g),j&&j(i.origUrl,h,g),y[i.url]=2})))}function h(a,b){function c(a,c){if(a){if(e(a))c||(j=function(){var a=[].slice.call(arguments);k.apply(this,a),l()}),g(a,j,b,0,h);else if(Object(a)===a)for(n in m=function(){var b=0,c;for(c in a)a.hasOwnProperty(c)&&b++;return b}(),a)a.hasOwnProperty(n)&&(!c&&!--m&&(d(j)?j=function(){var a=[].slice.call(arguments);k.apply(this,a),l()}:j[n]=function(a){return function(){var b=[].slice.call(arguments);a&&a.apply(this,b),l()}}(k[n])),g(a[n],j,b,n,h))}else!c&&l()}var h=!!a.test,i=a.load||a.both,j=a.callback||f,k=j,l=a.complete||f,m,n;c(h?a.yep:a.nope,!!i),i&&c(i)}var i,j,l=this.yepnope.loader;if(e(a))g(a,0,l,0);else if(w(a))for(i=0;i (function(w,d,s,l,i){w[l]=w[l]||[];w[l].push({'gtm.start':new Date().getTime(),event:'gtm.js'});var f=d.getElementsByTagName(s)[0];var j=d.createElement(s);var dl=l!='dataLayer'?'&l='+l:'';j.src='//www.googletagmanager.com/gtm.js?id='+i+dl;j.type='text/javascript';j.async=true;f.parentNode.insertBefore(j,f);})(window,document,'script','dataLayer','GTM-P4HH5NV'); Skip to main content Home About Submit ALERTS / RSS Search for this keyword Advanced Search Assessment of WBCT Use in Trauma Patients: A National audit for Radiology Resource Management and Limiting Radiation Exposure Latifah Al-Kandari , View ORCID Profile Michael Masoomi , Abdelhamid El Gargani , Mahdy Abass Hamza , Rami Mohamed Agha doi: https://doi.org/10.1101/2025.04.09.25325527 Latifah Al-Kandari 1 Department of Radiology, Adan Hospital, Al-Mosely Street, Hadiya, 46969, Ministry of Health , KW MD Find this author on Google Scholar Find this author on PubMed Search for this author on this site Michael Masoomi 1 Department of Radiology, Adan Hospital, Al-Mosely Street, Hadiya, 46969, Ministry of Health , KW 2 Department on Nuclear Medicine and Molecular Imaging, ADAN Hospital, Hadiya, 46969, Ministry of Health , KW PhD, MRCP(Lon) Find this author on Google Scholar Find this author on PubMed Search for this author on this site ORCID record for Michael Masoomi For correspondence: masoomim{at}sky.com Abdelhamid El Gargani 1 Department of Radiology, Adan Hospital, Al-Mosely Street, Hadiya, 46969, Ministry of Health , KW MD Find this author on Google Scholar Find this author on PubMed Search for this author on this site Mahdy Abass Hamza 1 Department of Radiology, Adan Hospital, Al-Mosely Street, Hadiya, 46969, Ministry of Health , KW MD Find this author on Google Scholar Find this author on PubMed Search for this author on this site Rami Mohamed Agha 1 Department of Radiology, Adan Hospital, Al-Mosely Street, Hadiya, 46969, Ministry of Health , KW MD Find this author on Google Scholar Find this author on PubMed Search for this author on this site Abstract Full Text Info/History Metrics Data/Code Preview PDF ABSTRACT Introduction Whole-body computed tomography (WBCT) is often indiscriminately used in trauma cases. This study aimed to assess the effective use of WBCT in trauma patients across emergency departments in State of Kuwait, evaluate the true incidence of critical injuries, and minimize unnecessary radiation exposure. Methods This multicenter, retrospective study across seven radiology departments included 1,367 trauma patients who underwent WBCT between 2022 and 2023, according to the American College of Radiology guidelines. Data on age, sex, injury mechanism, clinical indications, dose-length product, and WBCT findings were collected and analyzed using IBM SPSS version 25. Results Of 1,367 referrals, 578 (42.3%) had no significant findings, while 789 (57.7%) showed positive trauma-related results. Among the positive findings, 530 patients (38.8%) had major injuries, including solid organ and vertebral column injuries. The most common causes of WBCT referrals were road traffic accidents (RTAs) (911 patients, 66.6%), falls from height (FFH) (182 patients, 13%), falls of heavy objects (112 patients, 8%), head trauma (82 patients, 6%), buggy accidents (28 patients, 2%) and others. Negative WBCT findings had a mean effective dose (ED) of 19.98 ± 10.26 mSv. Conclusions Positive WBCT findings were seen in 57.7% of cases, but the 42.3% negative findings rate, was significantly higher than the 20.4% average reported in similar centers in Europe such as UK and Germany, which highlights the need to optimize WBCT usage in emergency department to reduce unnecessary scans and minimize radiation exposure. 1. Introduction Major trauma is the sixth leading cause of death worldwide and the leading cause of death and disability in the population aged 5 to 45 years [ 1 ]. The assessment is typically guided by strict protocols to quickly identify life-threatening conditions before conducting a comprehensive evaluation of other injuries. These protocols often prioritize the use of plain film radiography, ultrasonography and laboratory testing over comprehensive history and physical examination. Common initial imaging strategies include chest and pelvic radiographs and Focused Assessment with Sonography for Trauma (E-FAST), which are cost-effective and easy to perform but offer limited diagnostic accuracy. Several studies have shown that a thorough clinical examination, including the use of FAST, chest X-rays, and pelvic X-rays, can effectively exclude injuries, potentially avoiding unnecessary WBCT scans [ 2 - 3 ]. In contrast, whole-body computed tomography (WBCT) is often used as the primary assessment tool in trauma centers due to its high sensitivity and speed in detecting traumatic injuries [ 4 ]. In severely injured patients, WBCT provides accurate details about the extent of injuries and is also used to identify occult injuries in high-energy trauma patients who may not show obvious signs of injury [ 2 , 5 - 8 ]. The rationale for routine WBCT use is supported by studies showing a high risk of missing significant injuries in trauma patients without it. However, the routine use of WBCT in major trauma patients, even when no injury is clinically suspected, remains controversial, particularly from a radiation protection standpoint [ 3 ]. Studies have indicated that 1–3% of cancers globally are attributed to medical sources of radiation [ 9 - 11 ]. On average, WBCT exposes each patient to more than 20 mSv of effective radiation, which increases the risk of cancer mortality [ 3 ]. For a 35-year-old male, the risk of cancer mortality is estimated at 1 in 900 with a radiation dose of 24 mSv, while for an average 45-year-old adult, the risk is 1 in 1,250 with a radiation dose ranging from 10–20 mSv. [ 9 , 12 - 14 ]. While WBCT use in State of Kuwaitis aligned with the country’s broader healthcare objectives under State of Kuwait Vision 2035, which aims to modernize the healthcare system and improve patient outcomes, optimizing WBCT use is critical to achieving these goals without overburdening healthcare resources or exposing patients to unnecessary radiation risks. WBCT is widely available in government hospitals under the Ministry of Health (MOH). Its use is common in trauma cases, particularly for road traffic accidents (RTAs), which are a major public health issue in State of Kuwait[ 15 ]. Recently, there has been a shift from indiscriminate WBCT referrals for trauma patients, particularly those with high-energy trauma, towards a more risk-benefit-oriented approach. This approach incorporates clinical prediction rules to safely exclude WBCT in certain cases [ 16 ]. The aim of this study was to estimate the true incidence of clinical injuries referred to emergency departments at radiology centers in Kuwait. We hypothesised that this estimation could lead to more effective utilization of radiology resources, which are strained by the high volume of referral patients and could contribute to the optimisation of radiology healthcare services. 2. Methods This multicentric retrospective study included all seven radiology departments in Kuwait, examining 1367 trauma patients from 2022-2023 who referred from emergency departments. All trauma patients were initially managed and proceed to WBCT in accordance with the American College of Radiology guidelines for Major Blunt Trauma [ 17 ]. 2.1 Inclusion and Exclusion Criteria All patients with major traumatic event, hemodynamic stability and altered consciousness who were admitted to the emergency department were included in this study and underwent WBCT. Any other causes were excluded from this assessment. 2.2 Data Collection The proposed study received approval from the Ethics Committee of the relevant institution (MOH -KEC 1298). Data were collected from trauma patients admitted to the emergency departments of collaborative radiology centers. Consent was obtained as part of the standard clinical study. Three of the seven departments were equipped with GE CT-128, GE CT-256, and Siemens CT-128 scanners, while the remaining had Siemens CT-256 scanners. Patients received intravenous (IV) contrast-medium for the chest and abdomen. Post-imaging, all patient data were archived using PACS systems, with four departments utilizing Centricity, two using Agfa, and one using Siemens. Age, sex, mechanism of injury, clinical requests, clinical findings, and WBCT findings in the cervical spine, thoracolumbar spine, chest, abdomen, pelvis, and appendicular skeleton were recorded based on institutional reporting. Radiological results were initially classified into negative and positive findings. Positive findings were then categorized as major or minor injuries based on impact of energy, physiological disturbances, potential for life-threatening conditions and anatomical regions involved. The specification of WBCT scan acquisition parameters, dose-length product (DLP) values from the scanner-generated dose reports and a conversion factor that is, the region-specific normalized effective dose per DLP (mSv × mGy−1 × cm−1) [ 18 ] were used to calculate the effective dose (ED). The ED was estimated as the product of the DLP and the corresponding conversion factor (k): ED (mSv) ≈ k × DLP. For the whole-body scan, we used a k value (k=0.0093 mSv × mGy−1 × cm−1) [ 19 - 20 ]. CT Automatic exposure control (AEC) that modulates radiation exposure automatically and is widely used for optimization of radiation dose in CT were used by the departments [ 21 - 22 ]. The Sante DICOM viewer was utilized to retrieve all the relevant parameters. 2.3 Statistical Analysis A power calculation with a 10% margin of error and 95% confidence level indicated a minimum of 96 datasets per center. However, 200 WBCT trauma patient datasets were collected from each center for a more robust analysis. Pre-test clinical requests, including clinical signs, symptoms, injury mechanisms, and clinical queries, were compared with WBCT findings. Data analysis was conducted using IBM SPSS version 25.0. The Kolmogorov-Smirnov test assessed normality. Statistical significance was set at the 5% level. Chi-square, Student t-test, and Mann Whitney tests were used to compare categorical and quantitative datasets. 3. Results A total number of 1,367 cases were included and assessed in this study. The mean age of patients referred to all cohort departments was 33.54± 16.09 years, where 1,074 (78.6%) were males and 293 (21.4%) were females, and male to female ratio was 3.7:1. Out of 1,367 patients scan, 578 (42.3%) were reported as normal (negative finding), whereas 789 patients (57.7%) had positive trauma related radiological finding of which 530 patients were found to have a major injury (38.8%) including solid organ and vertebral column injuries ( Table 1 ). According to CT indication, 911 patients had been referred due to RTA (66.6%), 182 patients due to FFH (13%), 112 patients due to a fall of a heavy object (8%), 82 patients due to head trauma (6%), while 28 patients had injuries due to buggy accident (2%), and 24 patients had an injury due to assault (1.8%). The RTA, with a 66.6 % score was the most common indication for WBCT referral ( Table 2 ), ( Figure 1 ). Anatomical body regions that were affected according to the WBCT scan results were Head (48.7%), chest (31.1%), abdominal (10.2%), pelvis (7.6%), others (2.4%) ( Figure 2 ). View this table: View inline View popup Download powerpoint Table 1. Demographic characteristics and classification findings View this table: View inline View popup Download powerpoint Table 2. Mechanism of injury and WBCT indications-rate of positive and negative scans Download figure Open in new tab Fig. 1. Subset trauma Classifications and the rate of indications. Download figure Open in new tab Fig. 2. Anatomical body regions affected according to WBCT Description of WBCT scan finding and classification is given in Table 3 , where the most common (top 5) finding injuries across all the collaborative radiology departments were reported to be: head hemorrhage/edema/hematoma 293 (21.4%), fracture spine 242 (17.7%), fracture ribs/clavicle/scapula 191 (14.0%), fracture skull/face 173 (12.7%) and lung contusions 162 (11.9%). For the positive case category, the mean values for CTDI (Computed Tomography Dose Index) volume, scan length, and DLP (Dose Length Product) were recorded as 89.01 ± 59.80 mGy, 43.53 ± 30.13 cm, and 2410.52 ± 1112.07 mGy x cm, respectively. The effective dose was calculated, yielding a mean ED of 22.41 ± 10.35 mSv. In comparison, for patients with negative CT findings, the mean ED was 19.98 ± 10.26 mSv, which significantly overlapped the range of positive CT cases (22.41 ± 10.35 mSv), considering the standard deviations of ±10.26 and ±10.35 ( Table 4 ). Box plot comparisons of WBCT ED data across departments, showing overall consistency in dose distribution, with one department exhibiting greater variability in individual patient data, is illustrated in Figure 3 . The limited availability of data may have influenced the variability. View this table: View inline View popup Download powerpoint Table 3. Description of WBCT Scan findings and classifications View this table: View inline View popup Download powerpoint Table 4. Radiation characteristics and effective dose (ED) in trauma patients: Analysis across participating radiology departments Download figure Open in new tab Fig. 3. Box plot comparing WBCT effective dose (ED) across each radiology department, showing the overall pattern of dose distribution. 4. Discussion WBCT plays a crucial role in detecting injuries and assessing their severity for treatment planning. According to a study by Kalra et al. [ 23 ], up to 22% of injuries may be missed without WBCT; however, these findings are often derived from studies conducted in major trauma centers in the United States, which typically deal with a combination of blunt and penetrating trauma and a higher volume of severe cases [ 24 ]. Furthermore, there is no conclusive evidence that WBCT reduces trauma mortality [ 25 ]. To the best of our knowledge, this is the first large-scale multicenter study in the State of Kuwait to evaluate the use of WBCT in trauma patients within emergency departments. The occurrence of incidental findings, or “incidentalomas,” on CT scans has been reported in multiple studies, with some suggesting an incidence rate exceeding 50% [ 26 , 27 ]. A recent study from the New York trauma registry [ 28 ] found that 40% of trauma CTs had incidental findings. Of these, 63% were classified as Class 2 findings, which did not necessitate immediate attention but were not considered normal variations, thus requiring further investigation. Such incidental findings can be valuable for patients by enabling the early detection of significant underlying conditions. However, they may also lead to increased anxiety and healthcare costs due to additional investigations into abnormalities that may ultimately have no impact on the patient’s health [ 29 - 30 ]. Fear of missing significant pathology resulting in serious complications or outcomes and the worry of medicolegal ramifications are legitimate concerns [ 31 ]. A study by Caputo et al. [ 32 ] comparing the severity of injury, found that those undergoing WBCT had significantly higher Injury Severity Score (ISS) greater than 15 compared with those receiving selective scanning (29.72 vs. 26.46, p < 0.001, n = 23172). This might be misinterpreted as patients with more significant injuries being more likely to receive a WBCT scan, suggesting potential selection bias. However, both groups had ISS greater than 15, indicating that they were comparably severely injured. Meta-analyses of retrospective observational studies have reported that WBCT improves time to diagnosis and treatment, and reduces mortality in trauma patients, although these studies were heterogeneous and carried a high risk of bias [ 33 , 34 ]. Whole-body computed tomography for trauma has demonstrated a sensitivity of 95% and a specificity of 56% for detecting significant injuries [ 35 ]. The Randomized Study of Early Assessment by CT Scanning (REACT-2) is the only multicenter randomized controlled trial examining the use of WBCT in trauma. The trial included 1,403 severe trauma patients, randomized to either immediate WBCT or initial assessment with history, examination, chest X-ray (CXR), and FAST, followed by selective CT based on identified injuries. The study found no significant difference in mortality in 24 hours or 30 days. Subgroup analysis of polytrauma patients also showed no difference in mortality. However, REACT-2 demonstrated a reduction in time to diagnosis or treatment by 7 minutes overall, and 11 minutes in polytrauma patients. Despite some criticism, REACT-2 remains the highest quality evidence (level 2) for WBCT use in trauma [ 37 ]. Davies et al. [ 36 ] proposed a clinical scoring system considering multiple factors such as trauma to various body regions, Glasgow Coma Scale, hemodynamic and respiratory abnormalities, and injury mechanism. Several studies suggest using clinical prediction rules to safely omit unnecessary WBCTs, reducing radiation exposure and costs [ 29 , 38 - 39 ]. While WBCT is beneficial for severe polytrauma, high rates of WBCT in trauma patients with no acute findings raise concerns about overuse, unnecessary radiation exposure, and incidental findings requiring follow-up [ 40 ]. In recent retrospective studies of hemodynamically stable patients after high-risk motor vehicle collision, low rates of injury requiring treatment or follow-up were found in body regions without clinically suspected injury, suggesting that CT should perhaps be selected based on physical findings [ 41 ]. An example of this can be found in the study by Huber-Wagner et al. [ 38 ], where 3,924 trauma patients underwent computed tomography as part of their initial evaluation. Of these, 2,430 patients received organ-selective CT, while 1,494 underwent whole-body CT. The study found that the predicted mortality rate was significantly higher in the whole-body CT group (23.2% vs. 17.3%; p < 0.001) compared to the organ-selective CT group (17.1% vs. 17.5%; p = 0.66) [ 35 ]. These findings were further explored in a follow-up study conducted by the same authors in 2013, which included a total of 16,719 patients (9,233 in the whole-body CT group and 7,486 in the organ-selective CT group). The study revealed that the absolute mortality rate in the whole-body CT group was significantly lower than in the organ-selective CT group (17.4% vs. 21.4%; p < 0.001) [ 38 ]. Several meta-analyses have supported these results, reinforcing the idea that whole-body CT is a safe, effective, and efficient tool for surgical triage [ 32 , 34 , 35 , 42 ]. The inclusion of a whole-body CT protocol in the management of severely injured trauma patients has been shown to reduce time to a definitive diagnosis, improve the accuracy of patient selection for operative versus non-operative management, and lower overall radiation exposure. In our study, road traffic accidents (RTA) were the leading cause of injury among male patients (1074, 78.6%) and female patients (293, 21.4%) referred to ER departments. The overall rate of positive WBCT findings was 57.7%, with major cases at 38.8% and minor cases at 18.9%. While these findings provide valuable insights, they may lead to unnecessary follow-up investigations, increasing healthcare costs. A more selective approach would optimize resource use and allow for better allocation of funds to critical services. In countries like the UK, Germany, and Denmark, WBCT is applied more selectively, guided by clinical justification and reducing unnecessary radiation exposure [ 21 ]. In this study, we found that 42.3% of all WBCT findings were negative, which raising concerns about the unnecessary use of WBCT in radiology departments in Kuwait. This overuse can place significant strain on the 24/7 availability of skilled personnel and clinical services. In contrast, European countries such as the UK and Germany have reported lower percentages of negative findings (<20%) [ 43 ]. Additionally, we found that 73.9% of negative CT findings were associated with male patients, while 26.1% were associated with female patients. This discrepancy can be attributed to demographic factors, occupational risk exposure, and cultural norms. In Kuwait, males are more likely to engage in high-risk activities such as manual labor and driving, which results in a higher number of trauma cases requiring WBCT. Conversely, cultural norms may expose fewer females to such risks, thereby reducing their need for WBCT and contributing to the lower percentage of negative findings among them. This disparity reflects differences in trauma exposure demographics rather than overuse or inefficiency. Although no large-scale epidemiologic studies of cancer risk have been reported in association with CT scans, experts state that up to 2% of cancers in the United States may be attributed to radiation exposure from CT scans. The stochastic or risk of chance mutations of carcinogenesis is suggested to be a linear relation between dose and biologic effect with no safe threshold [ 44 ]. In our study, the related ED among the participated radiology departments were in the range of 11.92 to 28.9 mSv that are influenced by including the type of CT scanner, acquisition parameters, and the protocol in use. Patients with negative CT findings, with a mean ED of 19.98 ± 10.26, are exposed to radiation levels within the same range as those with positive CT findings (mean ED of 22.41 ± 10.35). The overlapping standard deviations (±10.26 and ±10.35) highlight that negative findings result in radiation exposure similar to positive findings, raising concerns about unnecessary radiation exposure in these patients. Two systematic reviews and analyses by Healy et al. [ 45 ] and Sierink et al. [ 46 ] found no difference in radiation mortality when comparing WBCT versus selective scanning of n = 8,180 and n = 5,470 trauma cases. To avoid unnecessary exposure and minimize the effect, adherence to the national diagnostic reference level (NDRL) which is set for CT diagnostic imaging based on the current facilities and practice in State of Kuwaitis recommended. In view of further optimisation and improving dose management, use of “Dose Watch” software solution that is a comprehensive, proactive radiation management program is recommended which can report the radiation dose delivered to patients during an examination and presents this data in an organized manner. Kuwait’s national healthcare goals, as outlined in Vision 2035 [ 47 ], focus on improving healthcare services and maximizing resource efficiency. The unnecessary use of WBCT conflicts with these objectives by increasing costs and diverting resources from other critical healthcare initiatives. This highlights the need for stricter adherence to clinical guidelines to ensure WBCT is used only when it offers clear benefit, aligning trauma care with Kuwait’s broader healthcare vision. Additionally, data from WBCT can help shape public health strategies, particularly in addressing high-risk factors like road traffic accidents, a major trauma cause in Kuwait. 5. Limitations Some limitations of our study include its retrospective design and the lack of consideration for injury severity. However, the impact of injury severity on the findings is likely minimal, as the two primary parameters—CT scan duration and image quality—are generally not affected by the patient’s condition. 6. Conclusions In this study, 57.7% of WBCT findings were positive, with major cases accounting for 38.8% and minor cases for 18.9%. While these findings provide valuable insights, they may lead to unnecessary follow-up investigations, placing strain on healthcare resources. The rate of negative findings (42.3%) was significantly higher than the 20.4% average reported in similar centers in the UK and Germany. Among negative findings, 73.9% were male, and 26.1% were female, reflecting demographic factors, occupational exposure, and cultural norms. Road traffic accidents (RTA) were the leading cause of injury. Although mortality rates were not addressed, appropriate selection criteria are crucial to minimize unnecessary scans. The overlapping mean ED for both positive and negative CT scans raise concerns about the necessity of WBCT, particularly for negative findings. Adherence to the national diagnostic reference level (NDRL) for CT imaging in State of Kuwaitis recommended. Additionally, WBCT data can play a pivotal role in shaping public health strategies, particularly addressing road traffic accidents, a major trauma cause in Kuwait. Data Availability All data produced in the present work are contained in the manuscript Authorship contributions Latifa Al-Kandari : Conceptualization, Methodology, overall setup and joint funding acquisition. Michael Masoomi : Data curation, editorial, funding acquisition, project administration, Writing-Original draft, writing review and editing communication. Acknowledgements The authors would like to acknowledge Hany Elrahman from the Medical Imaging Department at ADAN Hospital for his invaluable contribution in providing technical, computational services, and expertise. Furthermore, the authors express their appreciation to the following radiology departments in the State of State of Kuwait for their participation in providing trauma patient data (listed alphabetically): Al Adan Hospital – Ahmadi Health District; Farwaniya Hospital – Farwaniya Health District; Al-Jahra Hospital – Al Jahra Health District; Sabah Hospital – Al Sabah Specialized MED Center; Mubarak Al Kabeer Hospital – Hawally Health District; Amiri Hospital – Capital District; and Jaber Hospital – Capital District. Footnotes Collaborative Radiology Departments Al Adan Hospital – Ahmadi Health District KW Farwaniya Hospital – Farwaniya Health District -KW Al-Jahra Hospital – Al Jahra Health District -KW Sabah Hospital – Al Sabah Specialized Medical Center -KW Mubarak Al Kabeer Hospital – Hawalli Health District -KW Amiri Hospital –Capital District-KW Al Jaber Hospital - Capital District-KW Conflict of Interest The authors declare that they have no conflicts of interest related to the material discussed in this article. All authors are non-partner/non-partnership tracks/employees. Disclosure There is none to declare. Funding This study was supported by the Kuwait Foundation for the Advancement of Sciences (KFAS) [grant number PN22-13MM-1695] References [1]. ↵ Alberdi F , García I , Atutxa L , Zabarte M. Trauma and neurointensive care work group of SEMICYUC . Epidemiology of severe trauma. Med Intensiva . ( 2014 ) 38 : 580 – 8 . DOI: 10.1016/j.medin.2014.06.012 OpenUrl CrossRef PubMed [2]. ↵ Jones M , Davis P , Williams H. Clinical examinations in trauma: Importance in decision-making for imaging . J Emerg Med . ( 2017 ); 44 ( 1 ): 56 – 62 . OpenUrl [3]. ↵ Patel S , Kumar D. The impact of initial clinical evaluations in trauma care . Int J Trauma Rehabil . ( 2016 ); 12 ( 3 ): 78 – 85 . OpenUrl [4]. ↵ Long B , April MD , Summers S , Koyfman A. Whole body CT versus selective radiological imaging strategy in trauma: an evidence-based clinical review . The American journal of emergency medicine . ( 2017 ) 35 ( 9 ) 1356 – 62 . doi: 10.1016/j.ajem.2017.03.048 OpenUrl CrossRef PubMed [5]. ↵ Salim A , Sangthong B , Martin M , Brown C , Plurad D , Demetriades D. Whole body imaging in blunt multisystem trauma patients without obvious signs of injury: results of a prospective study . Archives of Surgery . ( 2006 ) 1141 ( 5 ) 468 – 75 . OpenUrl [6]. Leidner B , Adiels M , Aspelin P , Gullstrand P , Wallen S. Standardized CT examination of the Mult traumatized patient . Eur Radiol . ( 1998 ) 8 ( 9 ) 1630 – 8 . doi: 10.1007/s003300050601 . OpenUrl CrossRef PubMed Web of Science [7]. Leidner B , Adiels M , Aspelin P. [Computer tomography . Life-threatening injuries of the skull, thorax, abdomen and pelvis are diagnosed in 15 minutes] Lakartidningen . ( 1994 ) 91 ( 12 ) 1191 . OpenUrl PubMed [8]. ↵ Hessman MH , Hofmann A , Kreitner KF , Lott C , Rommens PM . The benefit of multislice CT in the emergency room management of polytraumatized patients . Acta Chir Belg . ( 2006 ) 106 ( 5 ) 500 – 7 . OpenUrl PubMed [9]. ↵ Arora R , Arora AJ . Justification of whole-body CT in polytrauma patients, can clinical examination help selecting patients? Quantitative Imaging in Medicine and Surgery . 2019 9 ( 4 ) 636 . doi: 10.21037/qims.2019.04.02 OpenUrl CrossRef [10]. Berrington de González A , Darby S. Risk of cancer from diagnostic X-rays: estimates for the UK and 14 other countries . Lancet ( 2004 ); 363 : 345 – 51 . doi: 10.1016/S0140-6736(04)15433-0 OpenUrl CrossRef PubMed Web of Science [11]. ↵ Brenner DJ , Hall EJ . Computed Tomography — An Increasing Source of Radiation Exposure . N Engl J Med ( 2007 ); 357 : 2277 – 84 . doi. 10.1056/NEJMra072149 OpenUrl CrossRef PubMed Web of Science [12]. ↵ Brenner DJ , Elliston CD . Estimated radiation risks potentially associated with full-body CT screening . Radiology ( 2004 ); 232 : 735 - 8 . doi. 10.1148/radiol.2323031095 OpenUrl CrossRef PubMed Web of Science [13]. Wutzler S , Marzi I. Routine total-body CT for trauma room patients—life saver or needless radiation exposure? J Thorac Dis ( 2016 ); 8 : 3040 – 1 . doi. 10.21037/jtd.2016.11.15 OpenUrl CrossRef PubMed [14]. ↵ Linder F , Mani K , Juhlin C , Eklöf H. Routine whole body CT of high energy trauma patients leads to excessive radiation exposure . Scand J Trauma Resusc Emerg Med ( 2016 ); 24 : 7 . Doi. 10.1186/s13049-016-0199-2 OpenUrl CrossRef PubMed [15]. ↵ Ministry of Health, Kuwait Annual Health Report . Available from: MOH Kuwait Website ( 2023 ). [16]. ↵ Corwin MT , Sheen L , Kuramoto A , Lamba R , Parthasarathy S , Holmes JF . Utilization of a clinical prediction rule for abdominal-pelvic CT scans in patients with blunt abdominal trauma . Emerg Radiol . ( 2014 ) 21 ( 6 ) 571 – 6 . doi: 10.1007/s10140-014-1233-1 . OpenUrl CrossRef PubMed [17]. ↵ ACR Appropriateness Criteria®: Major Blunt Trauma . Available at: https://acsearch.acr.org/docs/3102405/Narrative/ . Accessed May 12, 2024 . [18]. ↵ Bongartz G , Golding SJ , Jurik AG , et al. European Guidelines on quality criteria for computed tomography . Luxembourg, Luxembourg: European Commission , ( 2000 ) EUR 16262. [19]. ↵ International Commission on Radiological Protection . Diagnostic reference levels in medical imaging: review and additional advice. A web module produced by Committee 3 of the International Commission on Radiological Protection (ICRP) . Available at: http://www.icrp.org/docs/DRL_for_web.pdf . [Accessed January 2019 ]. [20]. ↵ Shrimpton PC , Jansen JTM , Harrison JD . Updated estimates of typical effective doses for common CT examinations in the UK following the 2011 national review . Br J Radiol . ( 2016 ) 89 20150346 . OpenUrl CrossRef PubMed [21]. ↵ Söderberg M , Gunnarsson M. Automatic exposure control in computed tomography-an evaluation of systems from different manufacturers . ActaRadiol . ( 2010 ) 51 625 – 34 . OpenUrl CrossRef PubMed Web of Science [22]. ↵ Lee CH , Goo JM , Ye HJ , Ye SJ , Park CM , et al. Radiation dose modulation techniques in the Multidetector CT era: from basics to practice . Radiographics . ( 2008 ) 28 1451 – 9 . OpenUrl CrossRef PubMed Web of Science [23]. ↵ Kalra MK , Maher MM , Toth TL , Schmidt B , Westerman BL , et al. Techniques and applications of automatic tube current modulation for CT . Radiology . ( 2004 ) 233 649 – 57 . OpenUrl CrossRef PubMed Web of Science [24]. ↵ Pfeifer R , Pape HC . Missed injuries in trauma patients: A literature review . Patient Safety Surg . ( 2008 ) 2 : 20 . doi: 10.1186/1754-9493-2-20 . OpenUrl CrossRef PubMed [25]. ↵ Fantus RJ , Nance ML . NTDB data points: Annual Report 2014: How severe is it? Bull Am Coll Surg . ( 2015 ) 100 ( 1 ) 61 – 2 . OpenUrl [26]. ↵ Ahmadinia K , Smucker JB , Nash CL , Vallier HA . Radiation exposure has increased in trauma patients over time . J Trauma Acute Care Surg . ( 2012 ) 72 ( 2 ) 410 – 5 . OpenUrl PubMed [27]. ↵ Paluska TR , Sise MJ , Sack DI , Sise CB , Egan MC , Biondi M. Incidental CT findings in trauma patients: incidence and implications for care of the injured . J Trauma ( 2007 ) 62 ( 1 ) 157 – 61 . OpenUrl CrossRef PubMed Web of Science [28]. ↵ Andrawes P , Picon AI , Shariff MA , et al. CT scan incidental findings in trauma patients: does it impact hospital length of stay? Trauma Surgery & Acute Care Open ( 2017 ) 2 ( 1 ) 1 – 6 . OpenUrl [29]. ↵ Maizlin ZV , Barnard SA , Gourlay WA , Brown JA . Economic and ethical impact of extrarenal findings on potential living kidney donor assessment with computed tomography angiography . Transpl Int ( 2007 ) 20 ( 4 ) 338 – 42 . OpenUrl CrossRef PubMed [30]. ↵ Berlin L. Potential legal ramifications of whole-body CT screening: taking a peek into Pandora’s box . AJR Am J Roentgenol ( 2003 ) 180 ( 2 ) 317 – 22 . OpenUrl PubMed [31]. ↵ Fletcher RH , Pignone M. Extracolonic findings with computed tomographic colonography: asset or liability? Arch Intern Med ( 2008 ) 168 ( 7 ): 685 – 6 . OpenUrl CrossRef PubMed Web of Science [32]. ↵ Caputo ND , Stahmer C , Lim G , Shah K. Whole-body computed tomographic scanning leads to better survival as opposed to selective scanning in trauma patients: a systematic review and meta-analysis . Journal of Trauma and Acute Care Surgery . ( 2014 ) 77 ( 4 ) 534 – 9 . doi: 10.1097/TA.0000000000000414 OpenUrl CrossRef PubMed [33]. ↵ Surendran A , Mori A , Varma DK , Gruen RL . Systematic review of the benefits and harms of whole-body computed tomography in the early management of multitrauma patients: are we getting the whole picture? J Trauma Acute Care Surg . ( 2014 ) 76 ( 2 ) 1122 – 1130 . OpenUrl CrossRef PubMed [34]. ↵ Jiang L , Ma Y , Jiang S , et al. Comparison of whole-body computed tomography vs. selective radiological imaging on outcomes in major trauma patients: a meta-analysis . Scand J Trauma Resusc Emerg Med . ( 2014 ) 22 : 54 . OpenUrl CrossRef PubMed [35]. ↵ Chidambaram S , Goh EL , Khan MA . A meta-analysis of the efficacy of whole-body computed tomography imaging in the management of trauma and injury . Injury . ( 2017 ) 48 ( 8 ) 1784 – 1793 . doi: 10.1016/j.injury.2017.06.003 OpenUrl CrossRef [36]. ↵ Davies RM , Scrimshire AB , Sweetman L , Anderton MJ , Holt EM . A decision tool for whole-body CT in major trauma that safely reduces unnecessary scanning and associated radiation risks: an initial exploratory analysis . Injury . ( 2016 ) 47 ( 1 ) 43 – 49 . doi: 10.1016/j.injury.2015.08.036 . OpenUrl CrossRef PubMed [37]. ↵ Sierink JC , Treskes K , Edwards MJ , Beuker BJ , Den Hartog D , Hohmann J , Dijkgraaf MG , Luitse JS , Beenen LF , Hollmann MW , Goslings JC . Immediate total-body CT scanning versus conventional imaging and selective CT scanning in patients with severe trauma (REACT-2): a randomised controlled trial . The Lancet . ( 2016 ) 13 388 ( 10045 ) 673 – 83 . OpenUrl [38]. ↵ Huber-Wagner S , Lefering R , Qvick LM , Körner M , Kay MV , Pfeifer KJ , Reiser M , Mutschler W , Kanz KG , Working Group on Polytrauma (NIS) of the German Trauma Society (DGU). Whole body computed tomography during trauma resuscitation–effect on outcome . Lancet . ( 2009 ) 373 ( 9673 ) 1455 – 61 . OpenUrl CrossRef PubMed Web of Science [39]. ↵ Kendall JL , Kestler AM , Whitaker KT , Adkisson MM , Haukoos JS . Blunt abdominal trauma patients are at very low risk for intra-abdominal injury after emergency department observation . West J Emerg Med . ( 2011 ) 12 ( 4 ) 496 – 504 . doi: 10.5811/westjem.2010.11.2016 . OpenUrl CrossRef PubMed [40]. ↵ Belabbas D , Auger M , Lederlin M , et al. Whole-body CT after motor vehicle crash: no benefit after high-energy impact and with normal physical examination . Radiology . ( 2019 ) 292 ( 1 ) 94 – 100 . doi: 10.1148/radiol.2019182806 . OpenUrl CrossRef PubMed [41]. ↵ Vandenberg J , Cullison K , Fowler SA , Parsons MS , McAndrew CM , Carpenter CR . Blunt thoracolumbar-spine trauma evaluation in the emergency department: a meta-analysis of diagnostic accuracy for history, physical examination, and imaging . J Emerg Med . ( 2019 ) 56 ( 2 ) 153 – 165 . doi: 10.1016/j.jemermed.2018.10.032 . OpenUrl CrossRef PubMed [42]. ↵ Ordoñez CA , Holguín A , García C , Parra MW , Angamarca E , Guzmán-Rodríguez M , et al. Implementation of a new Single-Pass Whole-Body Computed Tomography Protocol: Is it safe, effective and efficient in patients with severe trauma? Colomb Med (Cali) . ( 2020 ) 51 ( 1 ) e4224. 22. doi.org/ 10.25100/cm.v51i4.4362 OpenUrl CrossRef [43]. ↵ Hilbert , P. , et al. Whole-Body CT for Multiple Trauma Patients: State of the Art . Radiology Research and Practice . ( 2009 ) 1 – 8 . DOI: 10.1155/2009/934825 . OpenUrl CrossRef [44]. ↵ Rohner D , Bennett S , Samaratunaga C , Jewell E , Smith J , Gaskill-Shipley C , Lisco S. Cumulative total effective while-body radiation dose in critically ill patients . Chest . ( 2013 ) 144 ( 5 ) 1481Y1486 . doi: 10.1378/chest.12-2222 OpenUrl CrossRef [45]. ↵ Healy DA , Hegarty A , Feeley I , Clarke-Moloney M , Grace PA , Walsh SR . Systematic review and meta-analysis of routine total body CT compared with selective CT in trauma patients . Emerg Med J . ( 2014 ) 31 ( 2 ) 101Y108 . doi: 10.1136/emermed-2012-201892 OpenUrl CrossRef [46]. ↵ Sierink JC , Saltzherr TP , Edwards MJ , Beuker BJ , Patka P , Goslings JC ; REACT-2-studiegroep. Direct total body CT scan in multi-trauma patients [in Dutch] . Ned Tijdschr Geneeskd . ( 2012 ) 156 ( 30 ) A4897 . OpenUrl PubMed [47]. ↵ Government of Kuwait. Vision 2035: New Kuwait . Available at: New State of KuwaitVision 2035 . View the discussion thread. Back to top Previous Next Posted April 10, 2025. Download PDF Data/Code Email Thank you for your interest in spreading the word about medRxiv. NOTE: Your email address is requested solely to identify you as the sender of this article. Your Email * Your Name * Send To * Enter multiple addresses on separate lines or separate them with commas. You are going to email the following Assessment of WBCT Use in Trauma Patients: A National audit for Radiology Resource Management and Limiting Radiation Exposure Message Subject (Your Name) has forwarded a page to you from medRxiv Message Body (Your Name) thought you would like to see this page from the medRxiv website. Your Personal Message CAPTCHA This question is for testing whether or not you are a human visitor and to prevent automated spam submissions. Share Assessment of WBCT Use in Trauma Patients: A National audit for Radiology Resource Management and Limiting Radiation Exposure Latifah Al-Kandari , Michael Masoomi , Abdelhamid El Gargani , Mahdy Abass Hamza , Rami Mohamed Agha medRxiv 2025.04.09.25325527; doi: https://doi.org/10.1101/2025.04.09.25325527 Share This Article: Copy Citation Tools Assessment of WBCT Use in Trauma Patients: A National audit for Radiology Resource Management and Limiting Radiation Exposure Latifah Al-Kandari , Michael Masoomi , Abdelhamid El Gargani , Mahdy Abass Hamza , Rami Mohamed Agha medRxiv 2025.04.09.25325527; doi: https://doi.org/10.1101/2025.04.09.25325527 Citation Manager Formats BibTeX Bookends EasyBib EndNote (tagged) EndNote 8 (xml) Medlars Mendeley Papers RefWorks Tagged Ref Manager RIS Zotero Tweet Widget Facebook Like Google Plus One Subject Area Radiology and Imaging Subject Areas All Articles Addiction Medicine (568) Allergy and Immunology (863) Anesthesia (299) Cardiovascular Medicine (4425) Dentistry and Oral Medicine (443) Dermatology (382) Emergency Medicine (607) Endocrinology (including Diabetes Mellitus and Metabolic Disease) (1507) Epidemiology (15221) Forensic Medicine (30) Gastroenterology (1123) Genetic and Genomic Medicine (6588) Geriatric Medicine (667) Health Economics (997) Health Informatics (4524) Health Policy (1368) Health Systems and Quality Improvement (1612) Hematology (540) HIV/AIDS (1264) Infectious Diseases (except HIV/AIDS) (15910) Intensive Care and Critical Care Medicine (1103) Medical Education (623) Medical Ethics (145) Nephrology (667) Neurology (6588) Nursing (346) Nutrition (998) Obstetrics and Gynecology (1143) Occupational and Environmental Health (956) Oncology (3331) Ophthalmology (970) Orthopedics (369) Otolaryngology (420) Pain Medicine (435) Palliative Medicine (129) Pathology (663) Pediatrics (1690) Pharmacology and Therapeutics (691) Primary Care Research (710) Psychiatry and Clinical Psychology (5440) Public and Global Health (9219) Radiology and Imaging (2195) Rehabilitation Medicine and Physical Therapy (1369) Respiratory Medicine (1196) Rheumatology (593) Sexual and Reproductive Health (710) Sports Medicine (529) Surgery (710) Toxicology (99) Transplantation (289) Urology (265) (function(){function c(){var b=a.contentDocument||a.contentWindow.document;if(b){var d=b.createElement('script');d.innerHTML="window.__CF$cv$params={r:'9ffb15711a6909d6',t:'MTc3OTQ0NTE3OQ=='};var a=document.createElement('script');a.src='/cdn-cgi/challenge-platform/scripts/jsd/main.js';document.getElementsByTagName('head')[0].appendChild(a);";b.getElementsByTagName('head')[0].appendChild(d)}}if(document.body){var a=document.createElement('iframe');a.height=1;a.width=1;a.style.position='absolute';a.style.top=0;a.style.left=0;a.style.border='none';a.style.visibility='hidden';document.body.appendChild(a);if('loading'!==document.readyState)c();else if(window.addEventListener)document.addEventListener('DOMContentLoaded',c);else{var e=document.onreadystatechange||function(){};document.onreadystatechange=function(b){e(b);'loading'!==document.readyState&&(document.onreadystatechange=e,c())}}}})();

Text is read by the "Ask this paper" AI Q&A widget below. Extraction quality varies by source — PMC NXML preserves structure cleanly, OA-HTML may include some navigation residue, and OA-PDF can have broken hyphenation. The publisher copy (via DOI) is the canonical version.

My notes (saved in your browser only)

Ask this paper AI returns verbatim quotes from the full text · source: preprint-html

Answers must be backed by verbatim quotes from this paper's full text. Hallucinated quotes are dropped automatically; if no verbatim passage answers the question, we say so. How this works

Citation neighborhood (no data yet)

We don't have any in-corpus citations linked to this paper yet. This is a recent paper (2025) — citers typically take a year or two to land, and the OpenAlex reference graph may still be filling in.

Source provenance

europepmc
last seen: 2026-05-20T01:45:00.602351+00:00